Proteopedia:Featured SEL/6: Difference between revisions
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<tr><td><div class='scrolling '>'''Coronavirus Spike Protein | <tr><td><div class='scrolling '>'''Coronavirus Spike Protein Membrane Fusion'''<br> | ||
''by Eric Martz''<br> | ''by Eric Martz''<br> | ||
SARS-CoV-2 spike protein undergoes a dramatic conformational rearrangement that plays a central role in fusing the coronavirus membrane with the host cell membrane. Similar conformational transformations have been observed for the spike protein of SARS-CoV and mouse hepatitis virus, among others. These rearrangements also have much in common with the membrane fusion mechansism of influenza hemagglutinin. | SARS-CoV-2 spike protein undergoes a dramatic conformational rearrangement that plays a central role in fusing the coronavirus membrane with the host cell membrane. Similar conformational transformations have been observed for the spike protein of SARS-CoV and mouse hepatitis virus, among others. These rearrangements also have much in common with the membrane fusion mechansism of influenza hemagglutinin. | ||