5knr: Difference between revisions

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<StructureSection load='5knr' size='340' side='right'caption='[[5knr]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
<StructureSection load='5knr' size='340' side='right'caption='[[5knr]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5knr]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNR OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5KNR FirstGlance]. <br>
<table><tr><td colspan='2'>[[5knr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KNR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3L5:(2-{[2-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)ETHYL][2-(2-PHOSPHONOETHOXY)ETHYL]AMINO}ETHYL)PHOSPHONIC+ACID'>3L5</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.864&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5knp|5knp]], [[5knq|5knq]], [[5kny|5kny]], [[5kns|5kns]], [[5knv|5knv]], [[5knu|5knu]], [[5knt|5knt]], [[5knx|5knx]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3L5:(2-{[2-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)ETHYL][2-(2-PHOSPHONOETHOXY)ETHYL]AMINO}ETHYL)PHOSPHONIC+ACID'>3L5</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5knr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knr OCA], [http://pdbe.org/5knr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5knr RCSB], [http://www.ebi.ac.uk/pdbsum/5knr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5knr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5knr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knr OCA], [https://pdbe.org/5knr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5knr RCSB], [https://www.ebi.ac.uk/pdbsum/5knr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5knr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HPRT_ECOLI HPRT_ECOLI] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine.


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Eng, W S]]
[[Category: Eng WS]]
[[Category: Hockova, D]]
[[Category: Hockova D]]
[[Category: Janeba, Z]]
[[Category: Janeba Z]]
[[Category: Keough, D T]]
[[Category: Keough DT]]
[[Category: Complex]]
[[Category: Inhibitor]]
[[Category: Phosphoribosyltransferase]]
[[Category: Transferase-inhibitor complex]]

Latest revision as of 13:04, 27 September 2023

E. coli HPRT in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]-guanineE. coli HPRT in complexed with 9-[(N-phosphonoethyl-N-phosphonoethoxyethyl)-2-aminoethyl]-guanine

Structural highlights

5knr is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.864Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HPRT_ECOLI Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine.

See Also

5knr, resolution 2.86Å

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