SARS-CoV-2 spike protein fusion transformation: Difference between revisions

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The SARS-CoV-2 spike protein pre-fusion conformation is a homo-trimer, each chain having a length of  
The SARS-CoV-2 spike protein pre-fusion conformation is a homo-trimer, each chain having a mature length of 1,261 amino acids. This pre-fusion cryo-EM structure [[6XR8]] is complete except for 110 residues of the C-terminus, comprising 48 residues of the stem (heptad repeat 2 domain), a 23-residue trans-membrane domain, and a 39 residue cytoplasmic domain.




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Eric Martz, Karsten Theis