User:Eric Martz/MHC Answers: Difference between revisions
Eric Martz (talk | contribs) No edit summary |
Eric Martz (talk | contribs) No edit summary |
||
| Line 31: | Line 31: | ||
</li><br><li> | </li><br><li> | ||
<!--7--> | <!--7-->The peptide-binding groove of MHC class I has closed ends, and can accommodate only peptides of length 8-10 amino acids. In contrast, the groove if MHC class II has open ends, and binds peptides of 13 amino acids up to about 20 amino acids in length. | ||
</li><br><li> | </li><br><li> | ||
<!--8--> | <!--8-->Each individual has multiple alleles of MHC. These alleles vary in the amino acid sequences in their peptide-binding grooves, thus accommodating a wide range of peptides. In addition, the alpha chains of the MHC class II alleles can assemble with multiple possible beta chains, producing additional variation in the MHC class II grooves. | ||
</li><br><li> | </li><br><li> | ||