2xcx: Difference between revisions

<table><tr><td colspan='2'>[[2xcx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XCX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2XCX FirstGlance]. <br>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2xcv|2xcv]], [[2jc9|2jc9]], [[2xje|2xje]], [[2xjd|2xjd]], [[2xjf|2xjf]], [[2j2c|2j2c]], [[2xjb|2xjb]], [[2jcm|2jcm]], [[2xjc|2xjc]], [[2xcw|2xcw]]</td></tr>

<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2xcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xcx OCA], [http://pdbe.org/2xcx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xcx RCSB], [http://www.ebi.ac.uk/pdbsum/2xcx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xcx ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/5NTC_HUMAN 5NTC_HUMAN]] Autosomal recessive spastic paraplegia type 45. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:24482476</ref>   

[[http://www.uniprot.org/uniprot/5NTC_HUMAN 5NTC_HUMAN]] May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.