5k5m: Difference between revisions
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<StructureSection load='5k5m' size='340' side='right'caption='[[5k5m]], [[Resolution|resolution]] 2.01Å' scene=''> | <StructureSection load='5k5m' size='340' side='right'caption='[[5k5m]], [[Resolution|resolution]] 2.01Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5k5m]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5k5m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_2 Dengue virus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5K5M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5K5M FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=68T:5-[5-(3-HYDROXYPROP-1-YN-1-YL)THIOPHEN-2-YL]-2,4-DIMETHOXY-N-[(3-METHOXYPHENYL)SULFONYL]BENZAMIDE'>68T</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=68T:5-[5-(3-HYDROXYPROP-1-YN-1-YL)THIOPHEN-2-YL]-2,4-DIMETHOXY-N-[(3-METHOXYPHENYL)SULFONYL]BENZAMIDE'>68T</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5k5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5k5m OCA], [https://pdbe.org/5k5m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5k5m RCSB], [https://www.ebi.ac.uk/pdbsum/5k5m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5k5m ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A097PIE2_9FLAV A0A097PIE2_9FLAV] Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response.[ARBA:ARBA00024317] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Dengue virus 2]] | [[Category: Dengue virus 2]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arora | [[Category: Arora R]] | ||
[[Category: Benson | [[Category: Benson TE]] | ||