1bma: Difference between revisions

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{{STRUCTURE_1bma|  PDB=1bma  |  SCENE=  }}  
{{STRUCTURE_1bma|  PDB=1bma  |  SCENE=  }}  


'''BENZYL METHYL AMINIMIDE INHIBITOR COMPLEXED TO PORCINE PANCREATIC ELASTASE'''
===BENZYL METHYL AMINIMIDE INHIBITOR COMPLEXED TO PORCINE PANCREATIC ELASTASE===




==Overview==
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The crystal structure of an aminimide analog of a dipeptide inhibitor of porcine pancreatic elastase bound to its target serine protease has been solved. The peptidomimetic molecule binds in the same fashion as the class of dipeptides from which it was derived, making similar interactions with the subsites on the elastase surface. Because aminimides are readily synthesized from a wide variety of starting materials, they form the basis for a combinatorial chemistry approach to rational drug design.
The line below this paragraph, {{ABSTRACT_PUBMED_7604279}}, adds the Publication Abstract to the page
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{{ABSTRACT_PUBMED_7604279}}


==About this Structure==
==About this Structure==
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[[Category: Petsko, G A.]]
[[Category: Petsko, G A.]]
[[Category: Ringe, D.]]
[[Category: Ringe, D.]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 11:41:41 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:22:46 2008''

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