User:Dora Bonadio/Sandbox 1: Difference between revisions

Jump to navigation Jump to search
No edit summary
No edit summary
Line 3: Line 3:
<!-- Anything in this section will appear adjacent to the 3D structure and will be scrollable. -->
<!-- Anything in this section will appear adjacent to the 3D structure and will be scrollable. -->
== Introduction ==
== Introduction ==
The Mpro protease (also known as 3CLpro), is a viral non-structural protein from the virus SARS-CoV-2 <ref name="Crystal_structure">PMID:32198291</ref>, responsible for a major outbreak of the disease called [[Coronavirus Disease 2019 (COVID-19)]], declared pandemic by WHO in 11 march 2020 <ref name="WHO">WHO. COVID-19 situation reports [Internet]. [cited 2020 May 15]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports </ref>. It has an important role in virus replication, as it’s responsible for cleavage of the polyproteins of the virus, alongside with papain-like protease(s) <ref name="sars_mers">PMID:25039866</ref>.
The <scene name='84/845941/Monomer/1'>Mpro</scene> protease (also known as 3CLpro), is a viral non-structural protein from the virus SARS-CoV-2 <ref name="Crystal_structure">PMID:32198291</ref>, responsible for a major outbreak of the disease called [[Coronavirus Disease 2019 (COVID-19)]], declared pandemic by WHO in 11 march 2020 <ref name="WHO">WHO. COVID-19 situation reports [Internet]. [cited 2020 May 15]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports </ref>. It has an important role in virus replication, as it’s responsible for cleavage of the polyproteins of the virus, alongside with papain-like protease(s) <ref name="sars_mers">PMID:25039866</ref>.


== Function ==
== Function ==