5iu7: Difference between revisions

No edit summary
No edit summary
 
Line 3: Line 3:
<StructureSection load='5iu7' size='340' side='right'caption='[[5iu7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5iu7' size='340' side='right'caption='[[5iu7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5iu7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IU7 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IU7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5iu7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IU7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6DY:2-(FURAN-2-YL)-N~5~-[2-(4-PHENYLPIPERIDIN-1-YL)ETHYL][1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZINE-5,7-DIAMINE'>6DY</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5iu4|5iu4]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6DY:2-(FURAN-2-YL)-N~5~-[2-(4-PHENYLPIPERIDIN-1-YL)ETHYL][1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZINE-5,7-DIAMINE'>6DY</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=OLB:(2S)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLB</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ADORA2A, ADORA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iu7 OCA], [https://pdbe.org/5iu7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iu7 RCSB], [https://www.ebi.ac.uk/pdbsum/5iu7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iu7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5iu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iu7 OCA], [http://pdbe.org/5iu7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iu7 RCSB], [http://www.ebi.ac.uk/pdbsum/5iu7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iu7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  
[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.[https://www.uniprot.org/uniprot/C562_ECOLX C562_ECOLX] Electron-transport protein of unknown function.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 27: Line 26:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bortolato, A]]
[[Category: Bortolato A]]
[[Category: Cheng, R K.Y]]
[[Category: Cheng RKY]]
[[Category: Cooke, R M]]
[[Category: Cooke RM]]
[[Category: Deflorian, F]]
[[Category: Deflorian F]]
[[Category: Dore, A S]]
[[Category: Dore AS]]
[[Category: Errey, J C]]
[[Category: Errey JC]]
[[Category: Guo, D]]
[[Category: Guo D]]
[[Category: Heitman, L H]]
[[Category: Heitman LH]]
[[Category: Ijzerman, A P]]
[[Category: Ijzerman AP]]
[[Category: Marshall, F H]]
[[Category: Marshall FH]]
[[Category: Segala, E]]
[[Category: Segala E]]
[[Category: Chimera]]
[[Category: G-protein-coupled receptor]]
[[Category: Integral membrane protein]]
[[Category: Membrane protein]]
[[Category: Thermostabilizing mutation]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA