5imy: Difference between revisions

<table><tr><td colspan='2'>[[5imy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"corynebacterium_vaginale"_zinnemann_and_turner_1963 "corynebacterium vaginale" zinnemann and turner 1963] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IMY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IMY FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VLY, vly ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2702 "Corynebacterium vaginale" Zinnemann and Turner 1963]), CD59, MIC11, MIN1, MIN2, MIN3, MSK21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5imy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5imy OCA], [http://pdbe.org/5imy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5imy RCSB], [http://www.ebi.ac.uk/pdbsum/5imy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5imy ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/CD59_HUMAN CD59_HUMAN]] Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.  The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

[[Category: Corynebacterium vaginale zinnemann and turner 1963]]

[[Category: Human]]

[[Category: Lawrence, S L]]

[[Category: Morton, C J]]

[[Category: Parker, M W]]

[[Category: Toxin-toxin receptor complex]]