CD81: Difference between revisions
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
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== Function == | == Function == | ||
CD81 is a cell-surface protein involved in a variety of biological responses like adhesion, morphology, activation, proliferation | CD81 is a cell-surface protein involved in a variety of biological responses like adhesion, morphology, activation, proliferation and differentiation of of B- and T-cells<ref>PMID:9597125</ref>. CD81 belongs to the tetraspanin family - protein containing 4 transmembrane domains - which form microdomains in the cell surface with a variety of partner proteins. | ||
== Disease == | == Disease == | ||
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== Structural highlights == | == Structural highlights == | ||
The structure of the complex of human CD81 with mouse antibody shows interactions of the CD81 helix D with the antibody heavy chain and CD81 residues in helix C with the light chain<ref>PMID:32338599</ref>. | |||
</StructureSection> | </StructureSection> | ||