Nucleoside triphosphatase: Difference between revisions
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<StructureSection load='4a5a' size='340' side='right' caption=' | <StructureSection load='4a5a' size='340' side='right' caption='NTPase 2 tetramer complex with AMPPNP and Mg++ ion (green) (PDB code [[4a5a]])' scene=''> | ||
== Function == | == Function == | ||
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== Structural highlights == | == Structural highlights == | ||
The 3D structure of the complex between NTPase 2 and the ATP analog AMPPNP shows the NTPase structure composed of two domains. The structure contains 7 Cys-Cys bonds one of which located between domain I and II and reaching the diametrically positioned monomer was found by mutational analysis to be responsible for activation. The ATP analog - AMPPNP - is located in a cleft and forms interactions with domain I and domain II<ref>PMID:22130673</ref>. | |||
</StructureSection> | </StructureSection> | ||