Nucleoside triphosphatase: Difference between revisions

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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
<StructureSection load='4a5a' size='340' side='right' caption='Caption for this structure' scene=''>
10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue.


== Function ==
== Function ==


'''Nucleoside triphosphatase''' or '''nucleoside triphosphate diphosphohydrolase''' (NTPase)
'''Nucleoside triphosphatase''' or '''nucleoside triphosphate diphosphohydrolase''' (NTPase) is responsible for degradation of nucleotides to their monophosphate form.  NTPase is found in mammals and in pathogenic microbes.  In mammals NTPase hs a crucial role in regulation of purinergic signalling by hydrolysis of extracellular nucleotides.  The function of NTPase in pathogens is still unknown<ref>PMID:21638687</ref>.


== Disease ==
== Disease ==
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**[[6dt3]] - Nudi - ''Klebsiella pneumoniae'' <br />
**[[6dt3]] - Nudi - ''Klebsiella pneumoniae'' <br />
**[[3oga]], [[3n77]] - Nudi - ''Salmonella enterica'' <br />


*Nucleoside triphosphatase cancer-related
*Nucleoside triphosphatase cancer-related
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**[[3s86]] - NTPase - ''Thermotoga maritima'' <br />
**[[3s86]] - NTPase - ''Thermotoga maritima'' <br />
**[[3agr]] - NTPase - ''Neospora caninum'' <br />
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Alexander Berchansky