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Virus protease 3D structures: Difference between revisions

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**[[5hyo]], [[6noz]] – PEDVP – porcine epidemic diarrhea virus  <br />
**[[5hyo]], [[6noz]] – PEDVP – porcine epidemic diarrhea virus  <br />


*'''Coronavirus protease'''
*'''Echovirus 1 protease'''


**[[4wme]], [[4wmf]] – CVP (mutant)- coronavirus <br />
**[[5iyt]] – EV1P (mutant) + inhibitor – Echovirus 1 <br />


*'''SARS coronavirus protease'''
*'''Gastroentritis virus protease'''


**[[3e91]], [[3ea7]], [[3ea8]], [[3ea9]], [[3eaj]] – SCVP (mutant) – SARS coronavirus  <br />
**[[2amp]] – GEVP + inhibitor – gastroenteritis virus <br />
**[[2amd]], [[2amq]], [[2gx4]], [[2z9g]], [[2z9j]], [[2z9k]], [[2z9l]], [[2zu5]], [[4mds]], [[4tww]], [[4twy]] – SCVP + inhibitor  <br />


*'''SARS CoV-2 protease'''
*'''Southampton virus protease'''


**[[6y84]] – COV-19 <br />
**[[2iph]] – SVP + inhibitor – Southampton virus <br />
**[[6yb7]] – COV-19 <br />
**[[6lu7]] – COV-19 + inhibitor  N3 <br />


*'''SARS CoV-2 protease''' - PanDDA analysis group deposition of main protease fragment screens
*'''West Nile virus protease'''
**[[5rg2]] – COV-19 + inhibitor NCL-00025058 <br />
**[[5rf8]] – COV-19 + inhibitor Z271004858 <br />
**[[5rf9]] – COV-19 + inhibitor Z217038356 <br />
**[[5rfn]] – COV-19 + inhibitor PCM-0102868 <br />
**[[5r83]] – COV-19 + inhibitor Z44592329 <br />


*'''Murine coronavirus protease'''
**[[2ggv]] - WNVP (mutant) - West Nile virus<br />
**[[2ijo]] - WNVP (mutant) + BPTI<br />
**[[2yol]], [[5idk]], [[2fp7]] - WNVP + peptide inhibitor<br />
**[[3e90]] - WNVP + inhibitor<br />


**[[6jij]] – MCP + peptide inhibitor  <br />
*'''African swine fever virus protease'''


*'''Coronavirus HKU4 protease'''
**[[6ljb]], [[6lj9]] – ASFV – African swine fever virus<br />


**[[2ynb]] – CVHP + inhibitor – BAT coronavirus  <br />
*'''Norovirus protease residues 1101-1281'''


*'''Echovirus 1 protease'''
**[[2fyq]], [[2fyr]], [[3ur6]] – 3CLP<br />
**[[2lnc]] – 3CLP - NMR<br />
**[[2iph]] – 3CLP + peptide <br />
**[[5dg6]], [[5dgj]], [[5e0g]], [[5e0h]], [[5e0j]], [[5t6d]], [[5t6f]], [[5t6g]], [[5t61]], [[5t62]], [[4imq]], [[4imz]], [[4in1]], [[4in2]], [[4inh]], [[3ur9]], [[4xbb]], [[4xbc]], [[4xbd]], [[5wej]] – 3CLP + inhibitor <br />
**[[1wqs]] – 3CLP residues 1-173 + Hg


**[[5iyt]] – EV1P (mutant) + inhibitor – Echovirus 1  <br />
*Mouse Norovirus protease residues 995-1177


*'''Norovirus protease'''
**[[4ash]], [[4x2w]], [[4x2x]], [[4x2y]], [[4x2v]] – NS6 (mutant)<br />


**[[5e0g]], [[5e0h]], [[5e0j]] – NVP (mutant)+ peptide inhibitor – Norovirus  <br />
*'''SARS human corona virus 3C-like protease C-terminal 3241-3546'''
**[[3ur9]], [[4imq]], [[4xbb]], [[4xbc]], [[4xbd]], [[5dg6]], [[5dgj]], [[5tg1]], [[5tg2]] – NVP residues 1101-1281 + inhibitor  <br />


*'''Norovirus 3C-like protease'''
**[[1q2w]], [[2gt7]], [[1z1i]], [[2a5a]], [[2c3s]], [[2bx3]], [[2bx4]] , [[1uj1]], [[1uk2]], [[1uk3]], [[2duc]] – 3CLP – SARS-COV<br />
**[[5b6o]], [[3m3s]], [[3m3t]], [[3m3v]], [[3fzd]], [[3f9e]], [[3f9f]], [[3f9g]], [[3f9h]], [[3ea7]], [[3ea8]], [[3ea9]], [[3eaj]], [[3e91]], [[3ee7]], [[2qc2]], [[2qcy]], [[2pwx]], [[2gt8]], [[1z1j]], [[3aw1]] – 3CLP (mutant) – SARS-COV<br />
**[[2liz]] – 3CLP – SARS-COV - NMR<br />
**[[3ebn]] – 3CLP C-terminal 3429-3546<br />
**[[3d23]] – 3CLP + inhibitor – hCOV-HKU1<br />
**[[5gwy]] – 3CLP + inhibitor – hCOV-NL63<br />
**[[2amd]], [[2amq]], [[2amp]], [[1wof]], [[2ynb]], [[3atw]], [[3avz]], [[3iwm]], [[4yw3]], [[4tww]], [[4twy]] – 3CLP + inhibitor – SARS-COV<br />
**[[5c5n]], [[5c5o]] – 3CLP (mutant) + inhibitor – SARS-COV<br />
**[[2vj1]], [[3tit]], [[3tiu]] – 3CLP + unsaturated ester
**[[2zu2]], [[2zu4]], [[2zu5]], [[3tns]], [[3tnt]], [[3aw0]] – 3CLP + peptidomimetic compound<br />
**[[3d62]] – 3CLP + halometyl ketone inhibitor<br />
**[[2z9g]] – 3CLP + benzene + Hg<br />
**[[2z9j]], [[2z9k]], [[2z9l]] – 3CLP + Zn compound<br />
**[[2ops]] – 3CLP + phenylalanine derivative inhibitor<br />
**[[2z3c]], [[2z3d]], [[2z3e]], [[2gx4]], [[1uk4]] – 3CLP + peptide inhibitor<br />
**[[2gtb]] - 3CLP (mutant) + aza-peptide epoxide inhibitor<br />
**[[2a5i]], [[2a5k]] - 3CLP + aza-peptide epoxide inhibitor<br />
**[[2d2d]] – 3CLP + I2<br />


**[[1wqs]] – NVLP – chiba virus <br />
*'''SARS non-human corona virus 3C-like protease C-terminal'''


*'''Gastroentritis virus protease'''
**[[4zro]] – 3CLP + inhibitor – cat COV<br />
**[[2yna]] – 3CLP + inhibitor – bat COV-HKU4<br />


**[[2amp]] – GEVP + inhibitor – gastroenteritis virus <br />
*'''MERS corona virus protease C-terminal 3248-3553'''


*'''Southampton virus protease'''
**[[5c3n]] – ORF1A<br />
**[[4wmd]], [[4wme]], [[4wmf]] – ORF1A (mutant)<br />
**[[4ylu]] – ORF1A + inhibitor<br />
**[[5hih]] – ORF1A X domain 1109-1275<br />


**[[2iph]] – SVP + inhibitor – Southampton virus <br />
*'''MERS corona virus papain-like protease domain 1480-1811'''


*'''West Nile virus protease'''
**[[4rez]], [[4rna]], [[5ko3]] – ORF1AB  <br />
**[[4r3d]], [[4rsp]] – ORF1AB + inhibitor <br />
**[[4rf0]], [[4rf1]] – ORF1AB + ubiquitin/RPL40 <br />
**[[5v69]], [[5v6a]] – ORF1AB + ubiquitin <br />
**[[5tl6]], [[5tl7]] – ORF1AB + ubiquitin-like protein C-terminal <br />
**[[4wur]] – ORF1AB (mutant) + ubiquitin <br />


**[[2ggv]] - WNVP (mutant) - West Nile virus<br />
**[[2ijo]] - WNVP (mutant) + BPTI<br />
**[[2yol]], [[5idk]], [[2fp7]] - WNVP + peptide inhibitor<br />
**[[3e90]] - WNVP + inhibitor<br />


*'''African swine fever virus protease'''


**[[6ljb]], [[6lj9]] – ASFV – African swine fever virus<br />


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[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky
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