6gdi: Difference between revisions

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<SX load='6gdi' size='340' side='right' viewer='molstar' caption='[[6gdi]], [[Resolution|resolution]] 7.90&Aring;' scene=''>
<SX load='6gdi' size='340' side='right' viewer='molstar' caption='[[6gdi]], [[Resolution|resolution]] 7.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6gdi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GDI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6GDI FirstGlance]. <br>
<table><tr><td colspan='2'>[[6gdi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GDI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6GDI FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Abcb1a, Abcb4, Mdr1a, Mdr3, Pgy-3, Pgy3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Xenobiotic-transporting_ATPase Xenobiotic-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.44 3.6.3.44] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Xenobiotic-transporting_ATPase Xenobiotic-transporting ATPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.44 3.6.3.44] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6gdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gdi OCA], [http://pdbe.org/6gdi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gdi RCSB], [http://www.ebi.ac.uk/pdbsum/6gdi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gdi ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6gdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gdi OCA], [https://pdbe.org/6gdi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6gdi RCSB], [https://www.ebi.ac.uk/pdbsum/6gdi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6gdi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref>   
[[https://www.uniprot.org/uniprot/MDR1A_MOUSE MDR1A_MOUSE]] Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.<ref>PMID:19325113</ref>   
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

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