5m5h: Difference between revisions
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<SX load='5m5h' size='340' side='right' viewer='molstar' caption='[[5m5h]], [[Resolution|resolution]] 4.50Å' scene=''> | <SX load='5m5h' size='340' side='right' viewer='molstar' caption='[[5m5h]], [[Resolution|resolution]] 4.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5m5h]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5m5h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M5H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M5H FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m5h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m5h OCA], [https://pdbe.org/5m5h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m5h RCSB], [https://www.ebi.ac.uk/pdbsum/5m5h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m5h ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/YIDC_ECOLI YIDC_ECOLI] Inner membrane protein required for the insertion and/or proper folding and/or complex formation of integral inner membrane proteins. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex, as well as at least 2 lipoproteins. Its own insertion requires SRP and is Sec translocase-dependent. Essential for the integration of Sec-dependent subunit a of the F(0)ATP synthase, FtsQ and SecE proteins and for Sec-independent subunit c of the F(0)ATP synthase, M13 phage procoat and the N-terminus of leader peptidase Lep. Probably interacts directly with Sec-independent substrates. Sec-dependent protein FtsQ interacts first with SecY then subsequently with YidC. Sec-dependent LacY and MalF require YidC to acquire tertiary structure and stability, a chaperone-like function, but not for membrane insertion. Stable maltose transport copmplex formation (MalFGK(2)) also requires YidC. Partially complements a Streptococcus mutans yidC2 disruption mutant.<ref>PMID:10675323</ref> <ref>PMID:10949305</ref> <ref>PMID:12724529</ref> <ref>PMID:12950181</ref> <ref>PMID:15140892</ref> <ref>PMID:15067017</ref> <ref>PMID:17073462</ref> <ref>PMID:18456666</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</SX> | </SX> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Beckmann | [[Category: Beckmann R]] | ||
[[Category: Berninghausen | [[Category: Berninghausen O]] | ||
[[Category: Buschauer | [[Category: Buschauer R]] | ||
[[Category: Crevenna | [[Category: Crevenna AH]] | ||
[[Category: Kedrov | [[Category: Kedrov A]] | ||
[[Category: Lamb | [[Category: Lamb DC]] | ||
[[Category: Wickles S]] | |||
[[Category: Wickles | [[Category: Van der Sluis E]] | ||
[[Category: | |||