2xql: Difference between revisions
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<SX load='2xql' size='340' side='right' viewer='molstar' caption='[[2xql]], [[Resolution|resolution]] 19.50Å' scene=''> | <SX load='2xql' size='340' side='right' viewer='molstar' caption='[[2xql]], [[Resolution|resolution]] 19.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xql]] is a 10 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2xql]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQL FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2hio|2hio]], [[1tzy|1tzy]], [[1hq3|1hq3]], [[2aro|2aro]], [[1hio|1hio]], [[1eqz|1eqz]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2hio|2hio]], [[1tzy|1tzy]], [[1hq3|1hq3]], [[2aro|2aro]], [[1hio|1hio]], [[1eqz|1eqz]]</div></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xql OCA], [https://pdbe.org/2xql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xql RCSB], [https://www.ebi.ac.uk/pdbsum/2xql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xql ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/H2A4_CHICK H2A4_CHICK]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == |