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| ==Crystal structure of an adenine deaminase== | | ==Crystal structure of an adenine deaminase== |
| <StructureSection load='2ics' size='340' side='right'caption='[[2ics]], [[Resolution|resolution]] 2.30Å' scene=''> | | <StructureSection load='2ics' size='340' side='right'caption='[[2ics]]' scene=''> |
| == Structural highlights == | | == Structural highlights == |
| <table><tr><td colspan='2'>[[2ics]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICS OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2ICS FirstGlance]. <br> | | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ICS FirstGlance]. <br> |
| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ics FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ics OCA], [https://pdbe.org/2ics PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ics RCSB], [https://www.ebi.ac.uk/pdbsum/2ics PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ics ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2ics TOPSAN]</span></td></tr> |
| <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenine_deaminase Adenine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.2 3.5.4.2] </span></td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2ics FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ics OCA], [http://pdbe.org/2ics PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ics RCSB], [http://www.ebi.ac.uk/pdbsum/2ics PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ics ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/2ics TOPSAN]</span></td></tr> | |
| </table> | | </table> |
| == Function ==
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| [[http://www.uniprot.org/uniprot/DEACT_ENTFA DEACT_ENTFA]] Esterase that can catalyze the deacetylation of acetyl-(R)-mandelate, but with very low efficiency (in vitro).<ref>PMID:23214420</ref>
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| == Evolutionary Conservation == | | == Evolutionary Conservation == |
| [[Image:Consurf_key_small.gif|200px|right]] | | [[Image:Consurf_key_small.gif|200px|right]] |
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| ==See Also== | | ==See Also== |
| *[[Deaminase 3D structures|Deaminase 3D structures]] | | *[[Deaminase 3D structures|Deaminase 3D structures]] |
| == References ==
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| <references/>
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| __TOC__ | | __TOC__ |
| </StructureSection> | | </StructureSection> |
| [[Category: Enterococcus proteiformis thiercelin and jouhaud 1903]]
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| [[Category: Adenine deaminase]]
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| [[Category: Large Structures]] | | [[Category: Large Structures]] |
| [[Category: Burley, S K]] | | [[Category: Burley SK]] |
| [[Category: Kumaran, D]] | | [[Category: Kumaran D]] |
| [[Category: Structural genomic]]
| | [[Category: Sugadev R]] |
| [[Category: Sugadev, R]] | | [[Category: Swaminathan S]] |
| [[Category: Swaminathan, S]] | |
| [[Category: Adenine complex]]
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| [[Category: Amidohydrolase]]
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| [[Category: Binuclear zinc]]
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| [[Category: Hydrolase]]
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| [[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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| [[Category: PSI, Protein structure initiative]]
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| [[Category: Tim barrel]]
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