5d8e: Difference between revisions

<table><tr><td colspan='2'>[[5d8e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5D8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5D8E FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5d8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5d8e OCA], [https://pdbe.org/5d8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5d8e RCSB], [https://www.ebi.ac.uk/pdbsum/5d8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5d8e ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SOSB1_HUMAN SOSB1_HUMAN] Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.<ref>PMID:18449195</ref> <ref>PMID:19605351</ref> <ref>PMID:19683501</ref>  

[[Category: Homo sapiens]]

[[Category: Dong YH]]

[[Category: Gao ZQ]]

[[Category: Li YH]]