Sigma factor 3D structures

3D structures of sigma factor3D structures of sigma factor

Updated on 04-November-2020

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• Sigma factor
  • 1ku2 – TaSFA region 1.2-3.1 – Thermus aquaticus
    
  • 1ku3 – TaSFA region 4 (mutant)
    
  • 3les – TaSFA residues 93-271
    
  • 1sig – EcSF70 – Escherichia coli
    
  • 2mao – EcSFE region 2 - NMR
    
  • 6fi7 – EcSF38 - NMR
    
  • 1tty – TmSF70 region 4 – Thermotoga maritima
    
  • 2k6x – TmSF70 region 1.1 (mutant) - NMR
    
  • 2ahq – AaSF54 C terminal – Aquifex aeolicus - NMR
    
  • 2k9l, 2k9m – AaSF54 core domain - NMR
    
  • 3mzy – SFH – Fusobacterium nucleatum
    
  • 1h3l – ScSF N terminal – Streptomyces coelicolor
    
  • 5fgm – ScSFR region 4
    
  • 5mww – BsSFA region 1.1 - Bacillus subtilis - NMR
    
  • 5xe7 – MtSFJ – Mycobacterium tuberculosis
    
• Sigma factor complex with DNA
  • 3ugo, 3ugp - TaSFA region 2 + DNA
    
  • 1ku7 – TaSFA region 4 (mutant) + DNA
    
  • 4ki2 - TaSFA region 2-3 + DNA
    
  • 2h27 – EcSFE region 4 + DNA
    
  • 2map – EcSFE region 2 + DNA - NMR
    
  • 2o8k, 2o9l – AaS54 C terminal + DNA - NMR
    
  • 5ui5 – AaSF54 residues 61-398 + DNA
    
  • 6jhe – BsSFW region 4 + DNA
    
• Sigma factor complex with anti-sigma factor
  • 1tlh – EcSF70 region 4 + anti-σ factor
    
  • 1rp3, 1sc5 – AaSF28 + anti-σ factor FLGM
    
  • 6ivu – SF1 + anti-σ factor – Clostridium thermocellum
    
  • 5wur – BsSFW + anti-σ factor
    
  • 5uxx – SF + anti-σ factor – Bartonella quintana
    
  • 4nqw – MtSFK region 4 + anti-σ factor
    
• Sigma factor complex with protein
  • 3lev – TaSFA residues 93-271 + antibody
    
  • 1l9u – TaSFA region 1.1-4 + RNAP subunits α,β,β’,ω
    
  • 1or7 – EcSFE + σ-E factor negative regulatory protein
    
  • 4lup – EcSFE residues 3-92 + EcSF region 2
    
  • 2p7v – EcSF70 region 4 + regulator of σ D
    
  • 4yg2, 5uag, 5uaj, 5uaq – EcSF70 + RNAP subunits α,β,β’,ω
    
  • 5ui8 – EcSF45 + RNAP subunits α,β,β’,ω
    
  • 4mex, 4kmu, 4kn4, 4kn7, 5uac, 5uah, 5ual, 4zh3, 4zh4 – EcSF70 + RNAP subunits α,β,β’,ω + antibiotic
    
  • 4xsx, 4xsy, 4xsz – EcSF70 + RNAP subunits α,β,β’,ω + antibiotic
    
  • 6byu – EcSF70 + RNAP subunits α,β,β’,ω + ppApp
    
  • 4mey, 4ljz, 4lk1, 6cux – EcSF70 + RNAP subunits α,β,β’,ω
    
  • 6c9y, 6ca0 – EcSF70 + RNAP subunits α,β,β’,ω - Cryo EM
    
  • 5byh – EcSF45 + RNAP subunits α,β,β’,ω
    
  • 5nwt – EcSF54 + RNAP subunits α,β,β’,ω
    
  • 5w1s – EcSF70 + RNAP subunits α,β,β’ + TraR
    
  • 5vsw – EcSF70 + RNAP subunits α,β,β’ + DnaK suppressor protein
    
  • 5w1t – EcSF70 + RNAP subunits α,β,β’ + RpoZ + DnaK suppressor protein
    
  • 4lk0, 4llg, 4yfk, 4yfn, 4yfx, 4zh2 – EcSF70 + EcRNAP subunits α,β,β’,ω + RNAP inhibitor
    
  • 3hug – MtSFL + membrane protein
    
  • 4x8k – MtSFA region 2 + RBPA
    
  • 6onu, 6ono – MtSFA region 4 + WHIB1
    
  • 5zx3 – MtSFH + RNAP subunits α,β,β’,ω
    
  • 6fbv – MtSFA + RNAP subunits α,β,β’,ω - SP Cryo EM
    
  • 6c05, 6c06 – MtSFA + RNAP subunits α,β,β’,ω + RbpA - Cryo EM
    
  • 3wod, 2a6e, 2cw0, 5tmf – TtSFA + RNAP subunits α,β,β’,ω - Thermus thermophilus
    
  • 4mq9, 2a68, 2a69, 2a6h, 3dxj, 3eql – TtSF70 + RNAP subunits α,β,β’,ω + antibiotic
    
  • 2be5 – TtSF70 + RNAP subunits α,β,β’,ω + inhibitor
    
  • 6pfj, 6pfv – ScSF (mutant) + AMFC protein
    
  • 5tmc – TtSFA + RNAP subunits α,β,β’,ω + protein + G4P
    
  • 5xj0 – TtSFA + RNAP subunits α,β,β’,ω + GP39 + GP76
    
  • 5x22 – TtSFA + RNAP subunits α,β,β’,ω + GpA + CMPcPP
    
  • 4lk0, 4llg, 4yfk, 4yfn, 4yfx, 4zh2 – EcSF70 + EcRNAP subunits α,β,β’,ω + RNAP inhibitor
    
  • 4cxf – SF CNRH + CNRY – Cupriavidus metallidurans
    
  • 4g6d, 4g8x, 4g94 – SF70 region 4 + Orf067 – Staphylococcus aureus
    
  • 5yix – SF70 + GCRA - Caulobacter crescentus
    
  • 6in7 – SFH + ALGU – Pseudomonas aeruginosa
    
  • 6eyd – MsSFA + RNAP subunits α,β,β’,ω - Mycobacterium smegmatis – Cryo EM
    
  • 6dxo – SFA + BLDN – Streptomyces venezuelae
    
• Sigma factor complex with protein and DNA and RNA
  • 4oio, 4g7h, 4g7o, 4g7z, 4q4z, 4q5s – TtSF-A in reiterative transcription complex
    
  • 6kqd, 6kqe, 6kqf, 6kqg, 6kqh, 6kql, 6kqm, 6kqn, 6l74, 6lts – TtSF-A in initial transcription complex
    
  • 6wox, 6woy – TtSF-A in initial transcription complex + CPT
    
  • 1smy – TtSF + RNAP subunits α,β,β’,ω + G4P
    
  • 6p71, 6p70, 6oy7, 6oy6, 6oy5, 6ow3, 6ovy, 6ovr – TtSF-A in reiterative transcription complex
    
  • 5voi – TtSFA + TtRNAP subunits α,β,β’,ω + DNA
    
  • 5d4c – TtSF-A in transcription initiation complex + CTP + ATP
    
  • 5d4d – TtSF-A in transcription initiation complex + CTP + NAD
    
  • 5d4e – TtSF-A in transcription initiation complex + CTP + dephosphate-CoA
    
  • 3n97 – TaSF-A region 4 + RNAP subunits α + DNA
    
  • 4xlp, 4xlq, 5tjg – TaSF-A in transcription initiation complex
    
  • 1l9z – TaSF-A + RNAP subunits α,β,β’,ω + DNA – Cryo EM
    
  • 4xlr, 4xls – TaSF-A in transcription initiation complex + CarD-like transcriptional regulator
    
  • 1rio - TaSF-A region 4 + repression protein CI + DNA
    
  • 6p1k – EcSF-70 + EcRNAP subunits α,β,β’,ω - Cryo EM
    
  • 6vjs – EcSF-70 + EcRNAP subunits α,β,β’,ω
    
  • 3iyd – EcSF-70 in transcription initiation complex + catabolite gene activator
    
  • 4jk1, 4jk2, 4jkr – EcSF-70 + EcRNAP subunits α,β,β’,ω + G4P
    
  • 4yln, 4ylo, 4ylp, 6n62 – EcSF-70 in transcription initiation complex
    
  • 5nss – EcSF-54 + EcRNAP subunits α,β,β’,ω + phage shock protein F + DNA - Cryo EM
    
  • 5nsr, 6gh6, 6gh5, 6gfw – EcSF-54 + EcRNAP subunits α,β,β’,ω + DNA - Cryo EM
    
  • 6n61 – EcSF-70 + EcRNAP subunits α,β,β’,ω + capistruin + DNA
    
  • 6n60 – EcSF-70 + EcRNAP subunits α,β,β’,ω + microcin + DNA
    
  • 6p18 – EcSF-70 in transcription antitermination complex + protein Q
    
  • 6jnx – EcSF-70 in transcription antitermination complex + protein Q – Cryo EM
    
  • 6jbq – EcSF-E in transcription initiation complex – Cryo EM
    
  • 5vt0 – EcSF-70 + EcRNAP subunits α,β,β’,ω + RNA – Cryo EM
    
  • 6k4y – EcSF-70 + EcRNAP subunits α,β,β’,ω + anti-SF + MOTA + DNA – Cryo EM
    
  • 6ldi, 7c17 – EcSF-70 in transcription activation complex + Cuer – Cryo EM
    
  • 6pb4, 6pb5, 6pb6 – EcSF-70 in transcription activation complex + Crp – Cryo EM
    
  • 6n57, 6n58 – EcSF-70 in transcription initiation complex + Tsar – Cryo EM
    
  • 6psq, 6psr, 6pss, 6pst, 6psu, 6psv, 6psw – EcSF-70 in transcription initiation complex + Trar – Cryo EM
    
  • 6n4c, 6oul – EcSF-70 in transcription initiation complex – Cryo EM
    
  • 6wrg – EcSF-70 in transcription initiation complex + GTP – Cryo EM
    
  • 7chw, 7khb – EcSF-70 in transcription open promoter complex – Cryo EM
    
  • 7c97 – EcSF-70 in transcription open promoter complex + SSPA – Cryo EM
    
  • 7khi – EcSF-70 in transcription open promoter complex + DKSA + G4P – Cryo EM
    
  • 7khc – EcSF-70 in transcription closed promoter complex – Cryo EM
    
  • 6pmi, 6pmj – EcSF-28 in transcription initiation complex – Cryo EM
    
  • 6dcf – MtSF-A in transcription initiation complex + RBPA
    
  • 5uha – MtSF-A in transcription initiation complex
    
  • 6c04 – MtSF-A + RNAP subunits α,β,β’,ω + RbpA + DNA - Cryo EM
    
  • 5uhe, 5uhf – MtSF-A in transcription initiation complex + inhibitor
    
  • 6jcy, 6jcx, 5zx2 – MtSF-H in transcription initiation complex
    
  • 6kon, 6koo, 6kop, 6koq – MtSF-H in transcription initiation complex
    
  • 6dve, 6dvd – MtSF-L in transcription initiation complex
    
  • 6dvc, 6dvb, 6dv9, 6tye, 6tyf, 6tyg – MtSF-L in transcription initiation complex
    
  • 5tw1, 6cce – MsSF-A in transcription initiation complex + peptide - Mycobacterium smegmatis
    
  • 5vi8, 6vvv – MsSF-A in transcription initiation complex
    
  • 6ccv – MsSF-A in transcription initiation complex + peptide + RbpA + antibiotic
    
• Sigma factor complex with protein and DNA and antibiotics
  • 4oin, 4oip, 4oiq, 4oir – TtSF-A + RNAP subunits α,β,β’,ω + antibiotic + DNA
    
  • 6cuu – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + antibiotic
    
  • 5uhg – MtSF-A + MtRNAP subunits α,β,β’,ω + DNA + antibiotic + inhibitor
    
  • 5uhb – MtSF-A + MtRNAP subunits α,β,β’,ω + DNA + antibiotic
    
  • 6bzo – MtSF-A + RNAP subunits α,β,β’,ω + RbpA + DNA + antibiotic - Cryo EM
    
  • 6vvx, 6vvz – MtSF-A in transcription initiation complex + antibiotic – Cryo EM
    
  • 6vvy, 6vw0 – MtSF-A in transcription open promoter complex + antibiotic – Cryo EM
    
  • 6m7j – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + DNA + antibiotic – Cryo EM
    
  • 6eec, 6ee8, 6edt – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + CARD + DNA + antibiotic – Cryo EM
    
• Sigma factor complex with protein, DNA and RNA
  • 5vi5 – MsSF-A + MsRNAP subunits α,β,β’,ω + RbpA + DNA + RNA
    
  • 4xln – TaSF-A + RNAP subunits α,β,β’,ω + DNA + RNA
    
  • 5ipl, 5ipm, 5ipn – EcSF-38 + EcRNAP subunits α,β,β’,ω + DNA + RNA
    
  • 6b6h – EcSF-70 + EcRNAP subunits α,β,β’,ω + DNA + RNA - Cryo EM
    
  • 5e17, 5e18 – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + RNA
    
  • 5x22 – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + RNA + CMPPP
    
  • 5vo8 – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + RNA + GTP
    
  • 5x21 – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + RNA + antibiotic
    
  • 5i2d – TtSF-A + TtRNAP subunits α,β,β’,ω + transcriptional regulator + DNA + RNA
    
  • 5uh5, 5uh8, 5uh9 – MtSF-A + MtRNAP subunits α,β,β’,ω + DNA + RNA
    
  • 5uh6, 5uhc, 5uhd, 5x21 – MtSF-A + TtRNAP subunits α,β,β’,ω + DNA + RNA + antibiotic