5c6r: Difference between revisions

<table><tr><td colspan='2'>[[5c6r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C6R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C6R FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Asap1, Ddef1, Kiaa1249, Shag1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c6r OCA], [http://pdbe.org/5c6r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c6r RCSB], [http://www.ebi.ac.uk/pdbsum/5c6r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c6r ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/ASAP1_MOUSE ASAP1_MOUSE]] May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types. Plays a role in ciliogenesis (By similarity). Posseses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2.  

[[Category: Lk3 transgenic mice]]

[[Category: Tang, W K]]

[[Category: Xia, D]]

[[Category: Signaling protein]]