2e4m: Difference between revisions
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<StructureSection load='2e4m' size='340' side='right'caption='[[2e4m]], [[Resolution|resolution]] 1.85Å' scene=''> | <StructureSection load='2e4m' size='340' side='right'caption='[[2e4m]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2e4m]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2e4m]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_botulinum Clostridium botulinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E4M FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e4m OCA], [https://pdbe.org/2e4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e4m RCSB], [https://www.ebi.ac.uk/pdbsum/2e4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e4m ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/HA33_CLOBO HA33_CLOBO]] Protects the structural integrity of the neurotoxin; may increase internalization of the neurotoxin into the bloodstream of the host. Involved in binding to the small intestine through interactions with glycolipids and glycoproteins containing sialic acid moieties. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] |