4j2t: Difference between revisions

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<StructureSection load='4j2t' size='340' side='right'caption='[[4j2t]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='4j2t' size='340' side='right'caption='[[4j2t]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4j2t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J2T FirstGlance]. <br>
<table><tr><td colspan='2'>[[4j2t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J2T FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1HT:(3S,3AR,4S,6S,6AR,7S,8S,9BS)-6-(ACETYLOXY)-3A,4-BIS(BUTANOYLOXY)-3-HYDROXY-3,6,9-TRIMETHYL-8-{[(2E)-2-METHYLBUT-2-ENOYL]OXY}-2-OXO-2,3,3A,4,5,6,6A,7,8,9B-DECAHYDROAZULENO[4,5-B]FURAN-7-YL+OCTANOATE'>1HT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1HT:(3S,3AR,4S,6S,6AR,7S,8S,9BS)-6-(ACETYLOXY)-3A,4-BIS(BUTANOYLOXY)-3-HYDROXY-3,6,9-TRIMETHYL-8-{[(2E)-2-METHYLBUT-2-ENOYL]OXY}-2-OXO-2,3,3A,4,5,6,6A,7,8,9B-DECAHYDROAZULENO[4,5-B]FURAN-7-YL+OCTANOATE'>1HT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nal|3nal]], [[3nan|3nan]], [[3nam|3nam]], [[2c8k|2c8k]], [[3n5k|3n5k]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2t OCA], [https://pdbe.org/4j2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j2t RCSB], [https://www.ebi.ac.uk/pdbsum/4j2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2t ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j2t OCA], [http://pdbe.org/4j2t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j2t RCSB], [http://www.ebi.ac.uk/pdbsum/4j2t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j2t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Calcium-transporting ATPase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Autzen, H E]]
[[Category: Autzen HE]]
[[Category: Bonde, D F]]
[[Category: Bonde DF]]
[[Category: Bublitz, M]]
[[Category: Bublitz M]]
[[Category: Christensen, S B]]
[[Category: Christensen SB]]
[[Category: Dach, I]]
[[Category: Dach I]]
[[Category: Lie, M A]]
[[Category: Lie MA]]
[[Category: Liu, H]]
[[Category: Liu H]]
[[Category: Moller, J V]]
[[Category: Moller JV]]
[[Category: Nissen, P]]
[[Category: Nissen P]]
[[Category: Olesen, C]]
[[Category: Olesen C]]
[[Category: Paulsen, E S]]
[[Category: Paulsen ES]]
[[Category: Schiott, B]]
[[Category: Schiott B]]
[[Category: Sehgal, P]]
[[Category: Sehgal P]]
[[Category: Tenori, E]]
[[Category: Tenori E]]
[[Category: Villadsen, J]]
[[Category: Villadsen J]]
[[Category: Calcium transport]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: P-type atpase]]
[[Category: Thapsigargin analog]]

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