6p6a: Difference between revisions

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 <StructureSection load='6p6a' size='340' side='right'caption='[[6p6a]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6p6a]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P6A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P6A FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6p6a]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Neurospora_crassa_OR74A Neurospora crassa OR74A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6P6A FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5vqi|5vqi]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.151&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Kpna2, Rch1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6p6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p6a OCA], [https://pdbe.org/6p6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6p6a RCSB], [https://www.ebi.ac.uk/pdbsum/6p6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6p6a ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p6a OCA], [http://pdbe.org/6p6a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p6a RCSB], [http://www.ebi.ac.uk/pdbsum/6p6a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p6a ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/IMA1_MOUSE IMA1_MOUSE]] Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. [[http://www.uniprot.org/uniprot/NIT2_NEUCR NIT2_NEUCR]] Major nitrogen regulatory protein. During conditions of nitrogen limitation it turns on the expression of genes for enzymes which are required for the use of a variety of secondary nitrogen sources, including nitrates, purines, amino acids, and proteins.<ref>PMID:7612627</ref>
+[https://www.uniprot.org/uniprot/NIT2_NEUCR NIT2_NEUCR] Major nitrogen regulatory protein. During conditions of nitrogen limitation it turns on the expression of genes for enzymes which are required for the use of a variety of secondary nitrogen sources, including nitrates, purines, amino acids, and proteins.<ref>PMID:7612627</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 </div>
 <div class="pdbe-citations 6p6a" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Importin 3D structures|Importin 3D structures]]
 == References ==
 <references/>
@@ Line 24: / Line 26: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Lk3 transgenic mice]]
+[[Category: Mus musculus]]
-[[Category: Bernardes, N E]]
+[[Category: Neurospora crassa OR74A]]
-[[Category: Fontes, M R.M]]
+[[Category: Bernardes NE]]
-[[Category: Fukuda, C A]]
+[[Category: Fontes MRM]]
-[[Category: Oliveira, H C]]
+[[Category: Fukuda CA]]
-[[Category: Silva, T D]]
+[[Category: Oliveira HC]]
-[[Category: Importin alpha]]
+[[Category: Silva TD]]
-[[Category: Nuclear import]]
-[[Category: Transcription factor]]
-[[Category: Transport protein]]