1ahf: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:1ahf.gif|left|200px]]
+{{Seed}}
+[[Image:1ahf.png|left|200px]]
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 {{STRUCTURE_1ahf|  PDB=1ahf  |  SCENE=  }}
-'''ASPARTATE AMINOTRANSFERASE HEXAMUTANT'''
+===ASPARTATE AMINOTRANSFERASE HEXAMUTANT===
-==Overview==
+<!--
-Mutation of six residues of Escherichia coli aspartate aminotransferase results in substantial acquisition of the transamination properties of tyrosine amino-transferase without loss of aspartate transaminase activity. X-ray crystallographic analysis of key inhibitor complexes of the hexamutant reveals the structural basis for this substrate selectivity. It appears that tyrosine aminotransferase achieves nearly equal affinities for a wide range of amino acids by an unusual conformational switch. An active-site arginine residue either shifts its position to electrostatically interact with charged substrates or moves aside to allow access of aromatic ligands.
+The line below this paragraph, {{ABSTRACT_PUBMED_7664122}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 7664122 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_7664122}}
 ==About this Structure==
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 [[Category: Jansonius, J N.]]
 [[Category: Malashkevich, V N.]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 10:16:27 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:51:31 2008''