Basics of Protein Structure: Difference between revisions

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== Levels of Protein Structure ==
== Levels of Protein Structure ==
There are four different levels of protein structure.  The <scene name='60/604417/Ins_bead_backbone_labels/1'>primary structure</scene> is the amino acid sequence. The amino acids are connected by an amide bond, made from the amino group (NH2) of one amino acid, and the carboxylic acid (C=O) from another amino acid. The amino acids are linked in a repeating pattern. The backbone of the protein is the repeating N-C-C=O pattern, with the side chains projecting out from the backbone. The end with the free -NH2 group is called the N terminus, while the end with a free carboxylic acid is called the C terminus.  The sequence of amino acids is written from the N terminus to the C terminus.   
There are [[Four levels of protein structure|four different levels of protein structure]].  The <scene name='60/604417/Ins_bead_backbone_labels/1'>primary structure</scene> is the amino acid sequence. The amino acids are connected by an amide bond, made from the amino group (NH2) of one amino acid, and the carboxylic acid (C=O) from another amino acid. The amino acids are linked in a repeating pattern. The backbone of the protein is the repeating N-C-C=O pattern, with the side chains projecting out from the backbone. The end with the free -NH2 group is called the N terminus, while the end with a free carboxylic acid is called the C terminus.  The sequence of amino acids is written from the N terminus to the C terminus.   


The second level of structure is called secondary structure, and is the shape formed by short sequences of amino acids. This level of structure is stabilized by <scene name='57/575866/H_bond_a_helix/3'>hydrogen bonds</scene> along the <scene name='57/575866/Backbone/2'>backbone</scene>.   
The second level of structure is called secondary structure, and is the shape formed by short sequences of amino acids. This level of structure is stabilized by <scene name='57/575866/H_bond_a_helix/3'>hydrogen bonds</scene> along the <scene name='57/575866/Backbone/2'>backbone</scene>.   

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Joel L. Sussman, Ann Taylor, Eric Martz