4ast: Difference between revisions

<table><tr><td colspan='2'>[[4ast]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AST FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4aub|4aub]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ast FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ast OCA], [http://pdbe.org/4ast PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ast RCSB], [http://www.ebi.ac.uk/pdbsum/4ast PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ast ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/GPR_ECOLI GPR_ECOLI]] Catalyzes the stereospecific, NADPH-dependent reduction of L-glyceraldehyde 3-phosphate (L-GAP). The physiological role of gpr is the detoxification of L-GAP, which may be formed by non-enzymatic racemization of GAP. Also involved in the stress response as a methylglyoxal reductase which converts the toxic metabolite methylglyoxal to acetol in vitro and in vivo.<ref>PMID:12583903</ref> <ref>PMID:16077126</ref> <ref>PMID:18620424</ref>