2yjf: Difference between revisions
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<StructureSection load='2yjf' size='340' side='right'caption='[[2yjf]], [[Resolution|resolution]] 3.50Å' scene=''> | <StructureSection load='2yjf' size='340' side='right'caption='[[2yjf]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2yjf]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2yjf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/European_rabbit European rabbit] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YJF FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=LAB:LATRUNCULIN+B'>LAB</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=LAB:LATRUNCULIN+B'>LAB</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lcu|1lcu]], [[2a42|2a42]], [[2aso|2aso]], [[1ijj|1ijj]], [[1wua|1wua]], [[1o1a|1o1a]], [[1m8q|1m8q]], [[1o18|1o18]], [[1uy5|1uy5]], [[1rfq|1rfq]], [[1ma9|1ma9]], [[2d1k|2d1k]], [[2w49|2w49]], [[1rdw|1rdw]], [[2y83|2y83]], [[1o1b|1o1b]], [[1o1d|1o1d]], [[2a40|2a40]], [[2a5x|2a5x]], [[1qz5|1qz5]], [[2v52|2v52]], [[1nwk|1nwk]], [[1j6z|1j6z]], [[1sqk|1sqk]], [[1atn|1atn]], [[1s22|1s22]], [[1t44|1t44]], [[2ff3|2ff3]], [[1mvw|1mvw]], [[1eqy|1eqy]], [[2ff6|2ff6]], [[1o1f|1o1f]], [[2fxu|2fxu]], [[1kxp|1kxp]], [[2v51|2v51]], [[2asp|2asp]], [[1rgi|1rgi]], [[1o19|1o19]], [[1y64|1y64]], [[2yje|2yje]], [[1alm|1alm]], [[1o1e|1o1e]], [[1p8z|1p8z]], [[1esv|1esv]], [[1o1c|1o1c]], [[1h1v|1h1v]], [[2vcp|2vcp]], [[1o1g|1o1g]], [[2a3z|2a3z]], [[1lot|1lot]], [[2a41|2a41]], [[2asm|2asm]], [[1qz6|1qz6]], [[2vyp|2vyp]], [[2w4u|2w4u]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1lcu|1lcu]], [[2a42|2a42]], [[2aso|2aso]], [[1ijj|1ijj]], [[1wua|1wua]], [[1o1a|1o1a]], [[1m8q|1m8q]], [[1o18|1o18]], [[1uy5|1uy5]], [[1rfq|1rfq]], [[1ma9|1ma9]], [[2d1k|2d1k]], [[2w49|2w49]], [[1rdw|1rdw]], [[2y83|2y83]], [[1o1b|1o1b]], [[1o1d|1o1d]], [[2a40|2a40]], [[2a5x|2a5x]], [[1qz5|1qz5]], [[2v52|2v52]], [[1nwk|1nwk]], [[1j6z|1j6z]], [[1sqk|1sqk]], [[1atn|1atn]], [[1s22|1s22]], [[1t44|1t44]], [[2ff3|2ff3]], [[1mvw|1mvw]], [[1eqy|1eqy]], [[2ff6|2ff6]], [[1o1f|1o1f]], [[2fxu|2fxu]], [[1kxp|1kxp]], [[2v51|2v51]], [[2asp|2asp]], [[1rgi|1rgi]], [[1o19|1o19]], [[1y64|1y64]], [[2yje|2yje]], [[1alm|1alm]], [[1o1e|1o1e]], [[1p8z|1p8z]], [[1esv|1esv]], [[1o1c|1o1c]], [[1h1v|1h1v]], [[2vcp|2vcp]], [[1o1g|1o1g]], [[2a3z|2a3z]], [[1lot|1lot]], [[2a41|2a41]], [[2asm|2asm]], [[1qz6|1qz6]], [[2vyp|2vyp]], [[2w4u|2w4u]]</div></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yjf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yjf OCA], [https://pdbe.org/2yjf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yjf RCSB], [https://www.ebi.ac.uk/pdbsum/2yjf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yjf ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [[https://www.uniprot.org/uniprot/MKL1_MOUSE MKL1_MOUSE]] Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation.<ref>PMID:19350017</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Actin 3D structures|Actin 3D structures]] | *[[Actin 3D structures|Actin 3D structures]] | ||
*[[Transcriptional activator|Transcriptional activator]] | *[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> |