6in7: Difference between revisions

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<StructureSection load='6in7' size='340' side='right'caption='[[6in7]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
<StructureSection load='6in7' size='340' side='right'caption='[[6in7]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6in7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseae Pseae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IN7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IN7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6in7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IN7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NCA:NICOTINAMIDE'>NCA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mucA, PA0763 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE]), algU, algT, PA0762 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 PSEAE])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NCA:NICOTINAMIDE'>NCA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6in7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6in7 OCA], [http://pdbe.org/6in7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6in7 RCSB], [http://www.ebi.ac.uk/pdbsum/6in7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6in7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6in7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6in7 OCA], [https://pdbe.org/6in7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6in7 RCSB], [https://www.ebi.ac.uk/pdbsum/6in7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6in7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MUCA_PSEAE MUCA_PSEAE]] Negative regulator of the sigma factor AlgU. Plays a role in the differentiation of P.aeruginosa into the alginate-producing form. Inactivation of mucA causes a switch from the non-mucoid to mucoid state resulting in constitutive expression of alginate biosynthetic genes. [[http://www.uniprot.org/uniprot/RPSH_PSEAE RPSH_PSEAE]] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis.  
[https://www.uniprot.org/uniprot/RPSH_PSEAE RPSH_PSEAE] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor regulates genes such as algD, involved in alginate biosynthesis.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6in7" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6in7" style="background-color:#fffaf0;"></div>
==See Also==
*[[Sigma factor 3D structures|Sigma factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pseae]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Bartlam, M]]
[[Category: Bartlam M]]
[[Category: Li, S]]
[[Category: Li S]]
[[Category: Zhang, Q]]
[[Category: Zhang Q]]
[[Category: Sigma factor]]
[[Category: Transcription]]

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