4x8n: Difference between revisions

<table><tr><td colspan='2'>[[4x8n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X8N FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x8n OCA], [https://pdbe.org/4x8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x8n RCSB], [https://www.ebi.ac.uk/pdbsum/4x8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x8n ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ASH2L_HUMAN ASH2L_HUMAN] Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.<ref>PMID:12670868</ref> <ref>PMID:19556245</ref>  

[[Category: Homo sapiens]]

[[Category: Brand M]]

[[Category: Brunzelle JS]]

[[Category: Chaturvedi CP]]

[[Category: Couture J-F]]

[[Category: Shilatifard A]]

[[Category: Skiniotis G]]

[[Category: Zhang P]]