1up1: Difference between revisions

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<StructureSection load='1up1' size='340' side='right'caption='[[1up1]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1up1' size='340' side='right'caption='[[1up1]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1up1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UP1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UP1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1up1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UP1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UP1 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1up1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1up1 OCA], [http://pdbe.org/1up1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1up1 RCSB], [http://www.ebi.ac.uk/pdbsum/1up1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1up1 ProSAT]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1up1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1up1 OCA], [https://pdbe.org/1up1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1up1 RCSB], [https://www.ebi.ac.uk/pdbsum/1up1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1up1 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN]] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>  The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>   
[[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN]] Amyotrophic lateral sclerosis;Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>  The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>   
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN]] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref>   
[[https://www.uniprot.org/uniprot/ROA1_HUMAN ROA1_HUMAN]] Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and may modulate splice site selection. May play a role in HCV RNA replication.<ref>PMID:17229681</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

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