4uc1: Difference between revisions

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 <StructureSection load='4uc1' size='340' side='right'caption='[[4uc1]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4uc1]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"rhodococcus_capsulatus"_molisch_1907 "rhodococcus capsulatus" molisch 1907]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UC1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UC1 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4uc1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Cereibacter_sphaeroides Cereibacter sphaeroides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UC1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UC1 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MOE:METHOXY-ETHOXYL'>MOE</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=P4C:O-ACETALDEHYDYL-HEXAETHYLENE+GLYCOL'>P4C</scene>, <scene name='pdbligand=PP9:PROTOPORPHYRIN+IX'>PP9</scene>, <scene name='pdbligand=Z0P:(2S)-1-(HEXADECANOYLOXY)-3-HYDROXYPROPAN-2-YL+(11Z)-OCTADEC-11-ENOATE'>Z0P</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MOE:METHOXY-ETHOXYL'>MOE</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=P4C:O-ACETALDEHYDYL-HEXAETHYLENE+GLYCOL'>P4C</scene>, <scene name='pdbligand=PP9:PROTOPORPHYRIN+IX'>PP9</scene>, <scene name='pdbligand=Z0P:(2S)-1-(HEXADECANOYLOXY)-3-HYDROXYPROPAN-2-YL+(11Z)-OCTADEC-11-ENOATE'>Z0P</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uc2|4uc2]], [[4uc3|4uc3]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uc1 OCA], [https://pdbe.org/4uc1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uc1 RCSB], [https://www.ebi.ac.uk/pdbsum/4uc1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uc1 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uc1 OCA], [http://pdbe.org/4uc1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uc1 RCSB], [http://www.ebi.ac.uk/pdbsum/4uc1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uc1 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/TSPO_CERSP TSPO_CERSP] May play a role in the transmembrane transport of tetrapyrroles and similar compounds, and thereby contribute to the regulation of tetrapyrrole biosynthesis (PubMed:10409680). Binds tetrapyrroles and promotes the photooxidative degradation of protoporphyrin IX (PubMed:23651039). Binds protoporphyrin IX, hemin, and coproporphyrin III, but does not bind delta-aminolevulinic acid (PubMed:23952237, PubMed:20541505, PubMed:25635101). Can bind bilirubin, curcumin, gossypol, retinoic acid, cholesterol and the benzodiazepine receptor agonist PK-11195 (in vitro) (PubMed:23952237, PubMed:25635101). Plays a role in the response to low oxygen levels and in the regulation of the biosynthesis of photosynthetic pigments (PubMed:7673149, PubMed:10409680, PubMed:10681549).<ref>PMID:10681549</ref> <ref>PMID:20541505</ref> <ref>PMID:23651039</ref> <ref>PMID:23952237</ref> <ref>PMID:25635101</ref> <ref>PMID:7673149</ref> <ref>PMID:10409680</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 __TOC__
 </StructureSection>
-[[Category: Rhodococcus capsulatus molisch 1907]]
+[[Category: Cereibacter sphaeroides]]
 [[Category: Large Structures]]
-[[Category: Ferguson-Miller, S]]
+[[Category: Ferguson-Miller S]]
-[[Category: Garavito, R M]]
+[[Category: Garavito RM]]
-[[Category: Li, F]]
+[[Category: Li F]]
-[[Category: Liu, J]]
+[[Category: Liu J]]
-[[Category: Zheng, Y]]
+[[Category: Zheng Y]]
-[[Category: Transmembrane helice]]
-[[Category: Membrane protein]]
-[[Category: Mitochondria]]
-[[Category: Transport]]