6dko: Difference between revisions

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<StructureSection load='6dko' size='340' side='right'caption='[[6dko]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
<StructureSection load='6dko' size='340' side='right'caption='[[6dko]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6dko]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DKO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DKO FirstGlance]. <br>
<table><tr><td colspan='2'>[[6dko]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DKO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GXG:4-(2,6-difluorophenyl)-2,4-dioxobutanoic+acid'>GXG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.556&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">glcB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GXG:4-(2,6-difluorophenyl)-2,4-dioxobutanoic+acid'>GXG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Malate_synthase Malate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.9 2.3.3.9] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dko OCA], [https://pdbe.org/6dko PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dko RCSB], [https://www.ebi.ac.uk/pdbsum/6dko PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dko ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dko OCA], [http://pdbe.org/6dko PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dko RCSB], [http://www.ebi.ac.uk/pdbsum/6dko PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dko ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/A0A045ITM4_MYCTX A0A045ITM4_MYCTX]] Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.[HAMAP-Rule:MF_00641][SAAS:SAAS00078445]  
[https://www.uniprot.org/uniprot/MASZ_MYCTU MASZ_MYCTU] Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA (By similarity).[HAMAP-Rule:MF_00641]
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Malate synthase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Krieger, I V]]
[[Category: Krieger IV]]
[[Category: Sacchettini, J C]]
[[Category: Sacchettini JC]]
[[Category: Structural genomic]]
[[Category: Acetyltransferase]]
[[Category: Lyase]]
[[Category: Lyase-lyase inhibitor complex]]
[[Category: PSI, Protein structure initiative]]
[[Category: Tbsgc]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]

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