6ajk: Difference between revisions

<table><tr><td colspan='2'>[[6ajk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AJK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AJK FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.001&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ajk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ajk OCA], [https://pdbe.org/6ajk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ajk RCSB], [https://www.ebi.ac.uk/pdbsum/6ajk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ajk ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/TFB1M_HUMAN TFB1M_HUMAN] Mitochondrial non-syndromic sensorineural deafness. Variations in TFB1M may influence the clinical expression of aminoglycoside-induced deafness caused by the A1555G mutation in the mitochondrial 12S rRNA.

[https://www.uniprot.org/uniprot/TFB1M_HUMAN TFB1M_HUMAN] S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.<ref>PMID:11809803</ref> <ref>PMID:12068295</ref> <ref>PMID:12897151</ref>  

[[Category: Gong Q]]

[[Category: Li F]]

[[Category: Liu X]]

[[Category: Shen S]]

[[Category: Shi Y]]

[[Category: Wang C]]

[[Category: Wu J]]

[[Category: Wu P]]

[[Category: Zhang H]]