1a3n: Difference between revisions

Revision as of 15:56, 30 June 2008

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:1a3n.png

Template:STRUCTURE 1a3n

DEOXY HUMAN HEMOGLOBINDEOXY HUMAN HEMOGLOBIN

Template:ABSTRACT PUBMED 10930827

About this StructureAbout this Structure

1A3N is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

The structures of deoxy human haemoglobin and the mutant Hb Tyralpha42His at 120 K., Tame JR, Vallone B, Acta Crystallogr D Biol Crystallogr. 2000 Jul;56(Pt 7):805-11. PMID:10930827

Page seeded by OCA on Mon Jun 30 15:56:23 2008

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OCA

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-'''DEOXY HUMAN HEMOGLOBIN'''
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-==Overview==
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-The structures of deoxy human haemoglobin and an artificial mutant (Tyralpha42--&gt;His) have been solved at 120 K. While overall agreement between these structures and others in the PDB is very good, certain side chains are found to be shifted, absent from the electron-density map or in different rotamers. Non-crystallographic symmetry (NCS) is very well obeyed in the native protein, but not around the site of the changed residue in the mutant. NCS is also not obeyed by the water molecule invariably found in the alpha-chain haem pocket in room-temperature crystal structures of haemoglobin. At 120 K, this water molecule disappears from one alpha chain in the asymmetric unit but not the other.
+The line below this paragraph, {{ABSTRACT_PUBMED_10930827}}, adds the Publication Abstract to the page
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+{{ABSTRACT_PUBMED_10930827}}
 ==About this Structure==
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 [[Category: Oxygen transport]]
 [[Category: Respiratory protein]]
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