5t3t: Difference between revisions
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<StructureSection load='5t3t' size='340' side='right'caption='[[5t3t]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='5t3t' size='340' side='right'caption='[[5t3t]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5t3t]] is a 10 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5t3t]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Ebola_virus_-_Mayinga,_Zaire,_1976 Ebola virus - Mayinga, Zaire, 1976]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5T3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5T3T FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5t3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5t3t OCA], [https://pdbe.org/5t3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5t3t RCSB], [https://www.ebi.ac.uk/pdbsum/5t3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5t3t ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [https://www.uniprot.org/uniprot/VP30_EBOZM VP30_EBOZM] Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA stem-loop at the transcription start site of the first gene. Binds to RNA.<ref>PMID:12163572</ref> [https://www.uniprot.org/uniprot/NCAP_EBOZM NCAP_EBOZM] Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid and serves as template for transcription and replication. During replication, encapsidation by NP is coupled to RNA synthesis and all replicative products are resistant to nucleases. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Ebola virus - Mayinga, Zaire, 1976]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Abelson | [[Category: Abelson DM]] | ||
[[Category: Kirchdoerfer | [[Category: Kirchdoerfer RN]] | ||
[[Category: Moyer | [[Category: Moyer CL]] | ||
[[Category: Saphire | [[Category: Saphire EO]] | ||