1prq: Difference between revisions
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<StructureSection load='1prq' size='340' side='right'caption='[[1prq]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='1prq' size='340' side='right'caption='[[1prq]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1prq]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1prq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acaca Acaca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PRQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PRQ FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1prq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1prq OCA], [https://pdbe.org/1prq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1prq RCSB], [https://www.ebi.ac.uk/pdbsum/1prq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1prq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/PRO1A_ACACA PRO1A_ACACA]] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Profilin|Profilin]] | *[[Profilin 3D Structures|Profilin 3D Structures]] | ||
== References == | == References == | ||
<references/> | <references/> |