5fg8: Difference between revisions

No edit summary
No edit summary
 
Line 3: Line 3:
<StructureSection load='5fg8' size='340' side='right'caption='[[5fg8]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
<StructureSection load='5fg8' size='340' side='right'caption='[[5fg8]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5fg8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FG8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FG8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5fg8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FG8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FG8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.955&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CaMKII, CaM, CG18069 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME]), eag, CG10952 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fg8 OCA], [https://pdbe.org/5fg8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fg8 RCSB], [https://www.ebi.ac.uk/pdbsum/5fg8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fg8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fg8 OCA], [http://pdbe.org/5fg8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fg8 RCSB], [http://www.ebi.ac.uk/pdbsum/5fg8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fg8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KCC2A_DROME KCC2A_DROME]] A key regulator of plasticity in synaptic physiology and behavior, alterations in its activity produce pleiotrophic effects that involve synaptic transmission and development as well as various aspects of behavior. Directly modulates eag potassium channels.<ref>PMID:11980904</ref> <ref>PMID:14687552</ref> [[http://www.uniprot.org/uniprot/KCNAE_DROME KCNAE_DROME]] Structural component of a potassium channel. Mediates the potassium permeability of membranes; potassium current is regulated by CaMKII and CASK. Has a role in growth of the perineurial glial layer of the larval peripheral nerve.<ref>PMID:11517334</ref> <ref>PMID:11980904</ref> <ref>PMID:15901771</ref> <ref>PMID:1840699</ref> 
[https://www.uniprot.org/uniprot/KCC2A_DROME KCC2A_DROME] A key regulator of plasticity in synaptic physiology and behavior, alterations in its activity produce pleiotrophic effects that involve synaptic transmission and development as well as various aspects of behavior. Directly modulates eag potassium channels.<ref>PMID:11980904</ref> <ref>PMID:14687552</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 23: Line 22:
==See Also==
==See Also==
*[[Calcium/calmodulin dependent protein kinase 3D structures|Calcium/calmodulin dependent protein kinase 3D structures]]
*[[Calcium/calmodulin dependent protein kinase 3D structures|Calcium/calmodulin dependent protein kinase 3D structures]]
*[[Potassium Channel|Potassium Channel]]
*[[Potassium channel 3D structures|Potassium channel 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Calcium/calmodulin-dependent protein kinase]]
[[Category: Drosophila melanogaster]]
[[Category: Drome]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Castro-Rodrigues, A F]]
[[Category: Castro-Rodrigues AF]]
[[Category: Morais-Cabral, J H]]
[[Category: Morais-Cabral JH]]
[[Category: Complex]]
[[Category: Potassium channel]]
[[Category: Protein kinase]]
[[Category: Transferase]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA