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Structures used in the section above: [[1tll]]
Structures used in the section above: [[1tll]]


== 3D Structures of Nitric Oxide Synthase ==
= 3D Structures of Nitric Oxide Synthase =
[[Nitric Oxide Synthase 3D structures]]
[[Nitric Oxide Synthase 3D structures]]


</StructureSection>
</StructureSection>
== 3D Structures of Nitric Oxide Synthase ==


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
*Endothelial NOS
**[[3eah]] – h-eNOS OD - human<br />
**[[3nos]], [[4d1o]] – h-eNOS OD+arginine<br />
**[[1m9j]] – h-eNOS OD+chlorzoxazone<br />
**[[1m9k]], [[1m9r]], [[4d1p]], [[6av7]], [[6av6]], [[6nhf]], [[6nh8]], [[6nh7]], [[6nh6]], [[6nh5]], [[6nh4]], [[6nh3]], [[6nh2]], [[6nh1]], [[6cif]], [[6cie]] – h-eNOS OD+ inhibitor<br />
**[[1nsi]] - h-eNOS OD+ Zn<br />
**[[3nld]], [[3nle]], [[3nlf]], [[3nlg]], [[3jww]], [[3jwx]], [[3jwy]], [[3jwz]], [[3dqs]], [[3dqt]], [[3pnh]], [[4luw]] – b-eNOS OD+pyrrolidinomethyl pyridine derivative – bovine<br />
**[[1dm6]] – b-eNOS OD+guanidine derivative<br />
**[[3nlh]], [[3rqo]], [[3rqp]] – b-eNOS OD (mutant)+pyrrolidinomethyl aminopyridine derivative<br />
**[[1rs8]], [[1rs9]], [[1p6n]] – b-eNOS OD +dipeptide inhibitor<br />
**[[1nse]] – b-eNOS OD<br />
**[[1p6n]] – b-eNOS OD +dipeptide inhibitor<br />
**[[5nse]], [[1fol]], [[1foo]], [[1fop]], [[1dm7]], [[2nse]], [[3nse]], [[4nse]] – b-eNOS OD+arginine derivative<br />
**[[6nse]] – b-eNOS OD+canavanine<br />
**[[7nse]] – b-eNOS OD+ADMA<br />
**[[1i83]], [[1d1v]], [[1d1x]], [[1d1y]], [[1ed4]], [[9nse]] – b-eNOS OD+urea derivative<br />
**[[1dmj]], [[1dmk]] – b-eNOS OD+pterin derivative<br />
**[[1foi]], [[1dmi]], [[1i83]], [[3n5p]], [[3n5q]], [[3n5r]], [[3n5s]], [[3n5t]], [[3n5v]], [[3n5w]], [[3n5x]], [[3n5y]], [[3n5z]], [[3n60]], [[3n61]], [[3n62]], [[3n63]], [[3n64]], [[3n65]], [[3n66]], [[3n67]], [[3n68]], [[3n69]], [[3n6a]], [[3n6b]], [[3n6c]], [[3n6d]], [[3n6e]], [[3n6f]], [[3n6g]], [[3nlt]], [[3nlu]], [[3e7s]], [[5vv6]], [[5vv7]], [[5vv8]], [[5vv9]], [[4upq]], [[4upr]], [[4ups]], [[4upt]], [[5vva]], [[5vvb]], [[5vvc]], [[5vvd]], [[5vvg]], [[5vvn]], [[5uo8]], [[5uo9]], [[5uoa]], [[5uob]], [[5uoc]], [[5uod]], [[5fvy]], [[5fvz]], [[5fj2]], [[5fj3]], [[5adj]], [[5adk]], [[5adl]], [[5adm]], [[5adn]], [[4uh7]], [[4uh8]], [[4uh9]], [[4uha]], [[4d33]], [[4d34]], [[4d35]], [[4d36]], [[4d37]], [[4d38]], [[4d39]], [[4d3a]], [[4cul]], [[4cum]], [[4cun]], [[4cvg]], [[4cwv]], [[4cww]], [[4cwx]], [[4cwy]], [[4cty]], [[4ctz]], [[4cu0]], [[4cu1]] – b-eNOS OD+inhibitor<br />
**[[4cwz]], [[4cx0]], [[4cx1]], [[4cx2]]  – b-eNOS OD (mutant) +inhibitor<br />
**[[1d0c]], [[8nse]], [[1foj]], [[1ed5]], [[1d0o]], [[1d1w]] – b-eNOS OD+indazole derivative<br />
**[[1dm8]] – b-eNOS OD+triazole derivative<br />
**[[1ed6]] – b-eNOS OD+NO<br />
**[[1q2o]] – b-eNOS OD (mutant)+dipeptide inhibitor<br />
**[[1p6l]], [[1p6m]] – r-eNOS OD +dipeptide inhibitor - rat<br />
**[[3nli]] - r-eNOS OD (mutant)+pyrrolidinomethyl aminopyridine derivative<br />
**[[4jsk]], [[4jsl]], [[4jsm]], [[4imx]], [[4k5h]], [[4k5i]], [[4k5j]], [[4k5k]], [[4c3a]] – r-eNOS OD+ pyridine derivative<br />
**[[4kcp]], [[4kcq]], [[4kcr]], [[4kcs]] - r-eNOS OD heme domain +thiophene carboximidamide derivative<br />
*Neuronal NOS
**[[4uh5]], [[6av5]], [[6av4]], [[6av3]] - h-nNOS heme domain +inhibitor<br />
**[[4uh6]], [[4uch]], [[6av2]], [[6av1]], [[6av0]], [[6auz]], [[6auy]], [[5vv4]], [[5vv2]], [[5vv1]], [[5vuz]], [[5vuy]], [[5vux]], [[5vuw]], [[5vuv]], [[6nhb]], [[6nhc]], [[6cid]], [[6ng8]], [[6ngi]], [[6ngh]], [[6ngf]], [[6nge]], [[6ngd]], [[6ngc]], [[6ngb]], [[6nga]], [[6ng7]], [[6ng6]], [[6ng5]], [[6ng4]], [[6ng2]], [[6ng1]], [[6cic]] - h-nNOS heme domain + inhibitor<br />
**[[4d1n]] - h-nNOS heme domain (mutant) + arginine<br />
**[[2hx2]] – b-nNOS OD+nitroguanidine derivative<br />
**[[3nlv]], [[3nlw]], [[3nlx]], [[3nly]], [[3nlz]], [[3nm0]], [[4uh7]], [[4uh8]], [[4uh9]], [[4uha]] - b-nNOS OD + inhibitor<br />
**[[3nli]], [[3nlj]], [[3nlk]], [[3nln]], [[3nlo]], [[3nlp]], [[3nlq]], [[3nlr]], [[3jws]], [[3jwt]], [[3jwu]], [[3jwv]], [[3jx0]], [[3jx1]], [[3jx2]], [[3jx3]], [[3jx4]], [[3jx5]], [[3jx6]], [[3pne]], [[3pnf]], [[3png]], [[3svp]], [[3svq]] - r-nNOS OD (mutant)+ pyridine derivative – rat<br />
**[[3nlm]], [[3nny]], [[3nnz]], [[3n2r]], [[3b3o]], [[3b3p]], [[3b3m]], [[3b3n]], [[3rqj]], [[3rqk]], [[3rql]], [[3rqm]], [[3rqn]], [[3tyl]], [[3tym]], [[3tyn]], [[3tyo]], [[4ims]], [[4imt]], [[4imu]], [[4imw]], [[4jse]], [[4jsf]], [[4jsg]], [[4jsh]], [[4jsi]], [[4jsj]], [[4k5d]], [[4k5e]], [[4k5f]], [[4k5g]], [[4lux]] - r-nNOS OD+ pyridine derivative<br />
**[[4gqe]]  – r-nNOS OD + norvaline derivative<br />
**[[1om4]], [[1k2r]], [[1k2s]], [[1lzx]], [[2hx4]], [[1zvl]], [[1qw6]], [[4fvw]], [[4fvx]], [[4fvy]], [[4fvz]], [[4fw0]] - r-nNOS OD+arginine derivative<br />
**[[4cam]], [[4can]], [[4cao]], [[4cap]], [[4caq]], [[4car]], [[4cdt]], [[4cft]]  – r-nNOS OD heme domain + quinoline derivative<br />
**[[1k2t]], [[1k2u]] – r-nNOS OD+thiourea derivative<br />
**[[1om5]] – r-nNOS OD+indazole derivative<br />
**[[1lzz]], [[1m00]], [[2hx3]]– r-nNOS OD+guanidine derivative<br />
**[[4kch]], [[4kci]], [[4kcj]], [[4kck]], [[4kcl]], [[4kcm]], [[4kcn]], [[4kco]] - r-nNOS OD heme domain +thiophene carboximidamide derivative<br />
**[[3fc5]], [[1zvi]] – r-nNOS OD<br />
**[[1qau]] - r-nNOS OD PDZ domain<br />
**[[1qav]], [[4hop]] - r-nNOS OD PDZ domain + α-1 syntrophin<br />
**[[1qwc]], [[3q99]], [[3q9a]], [[1mmv]], [[1mmw]], [[3dqr]], [[3ufo]], [[3ufp]], [[3ufq]], [[3ufr]], [[3ufs]], [[3uft]], [[3ufu]], [[3ufv]], [[3ufw]], [[4eux]], [[5vui]], [[4upm]], [[4upn]], [[4upo]], [[4upp]], [[5vuk]], [[5vul]], [[5vum]], [[5vun]], [[5vuo]], [[5vup]], [[5vuq]], [[5vur]], [[5vus]], [[5vut]], [[5vuu]], [[5unr]], [[5unt]], [[5unu]], [[5unv]], [[5unw]], [[5unx]], [[5uny]], [[5unz]], [[5uo0]], [[5fw0]], [[5fvo]], [[5fvp]], [[5fvq]], [[5fvr]], [[5fvs]], [[5fvt]], [[5agk]], [[5agl]], [[5agm]], [[5agn]], [[5ago]], [[5agp]], [[4v3v]], [[4v3w]], [[4v3x]], [[4v3y]], [[4v3z]], [[5ad4]], [[5ad5]], [[5ad6]], [[5ad7]], [[5ad8]], [[5ad9]], [[5ada]], [[5adb]], [[5adc]], [[4ugz]], [[4d33]], [[4d34]], [[4d35]], [[4d2y]], [[4d1z]], [[4d30]], [[4d31]], [[4uh4]], [[4d7o]], [[4d3b]], [[4d32]], [[4ctp]], [[4ctq]], [[4ctr]], [[4ctt]], [[4ctu]], [[4ctv]], [[4c39]], [[6aux]], [[6auw]], [[6auv]], [[6auu]], [[6aut]], [[6aur]], [[6auq]], [[5vuj]], [[4uh3]], [[4uh2]], [[4uh1]], [[4uh0]], [[4d2z]], [[4ctx]], [[4ctw]], [[6nhe]], [[6nhd]], [[6nh0]], [[6ngz]], [[6ngy]], [[6ngx]], [[6ngw]], [[6ngv]], [[6ngu]], [[6ngt]], [[6ngs]], [[6ngr]], [[6ngq]], [[6ngp]], [[6ngn]], [[6ngm]], [[6ngl]], [[6ngk]], [[6ngj]] – r-nNOS OD+inhibitor<br />
**[[5vv0]], [[5vv3]], [[5vv5]], [[5uns]], [[5uo1]], [[5uo2]], [[5uo3]], [[5uo4]], [[5uo5]], [[5uo6]], [[5uo7]], [[5g0n]], [[5g0p]], [[5fvu]], [[5fvv]], [[5fvx]], [[5fvw]], [[5fvx]], [[4v3u]], [[5add]], [[5ade]], [[5adf]], [[5adg]], [[5adi]], [[4cx3]], [[4cx4]], [[4cx5]], [[4cx6]], [[6aus]], [[5g0o]] – r-nNOS OD (mutant) +inhibitor<br />
**[[3jt3]], [[3jt4]], [[3jt5]], [[3jt6]], [[3jt7]], [[3jt8]], [[3jt9]], [[3jta]] – r-nNOS OD+ornithine derivative<br />
**[[3hsn]] – r-nNOS OD+NHA+CO<br />
**[[3hso]], [[3hsp]] -  r-nNOS OD+NHA+NO<br />
**[[2g6h]], [[2g6i]], [[2g6j]] – r-nNOS OD+pterin derivative<br />
**[[2g6k]], [[2g6l]] – r-nNOS OD+pterin derivative+NO<br />
**[[2g6m]], [[2g6n]], [[2g6o]] – r-nNOS OD+pterin derivative+CO<br />
**[[1zzq]], [[1zzr]], [[1zzs]], [[1zzt]], [[1zzu]], [[1p6k]] – r-nNOS OD (mutant)+dipeptide inhibitor<br />
**[[1rs6]], [[1rs7]], [[1p6h]], [[1p6i]], [[1p6j]] – r-nNOS OD +dipeptide inhibitor<br />
**[[1b8q]] – r-nNOS PDZ domain + heptapeptide<br />
**[[1f20]] - r-nNOS FAD/NADP domain<br />
**[[1vag]] – m-nNOS OD+inhibitor - mouse<br />
*Inducible NOS
**[[3hr4]] – h-iNOS residues 503-715+calmodulin <br />
**[[3e7g]] – h-iNOS residues 82-505+inhibitor<br />
**[[3ej8]] – h-iNOS OD+imidazole<br />
**[[4nos]], [[4cx7]] – h-iNOS OD+inhibitor<br />
**[[1nsi]] – h-iNOS OD+arginine<br />
**[[2nsi]] – h-iNOS OD+thiourea derivative<br />
**[[3nqs]], [[3e65]], [[3eai]], [[3ebd]], [[3ebf]], [[1r35]], [[2nod]]  – m-iNOS OD + pterin derivative<br />
**[[1jwj]], [[1jwk]] – m-iNOS OD (mutant)+ pterin derivative<br />
**[[4ux6]] – m-iNOS OD + pterin derivative + inhibitor<br />
**[[2bhj]] – m-iNOS OD+coumarin<br />
**[[3nod]] – m-iNOS OD+product analog<br />
**[[1noc]] – m-iNOS OD+chloramphenicol acetyltransferase<br />
**[[3e67]] – m-iNOS OD+4-MAP<br />
**[[3e68]], [[3e6l]], [[3e6n]], [[3e6o]], [[3e6t]], [[3e7i]], [[3e7m]], [[3e7t]], [[1vaf]], [[1qw5]], [[1dd7]], [[2y37]] – m-iNOS OD+inhibitor <br />
**[[2orq]], [[2orr]], [[2ors]], [[2ort]], [[2oro]], [[2orp]], [[1nos]], [[3nw2]] – m-iNOS OD+imidazole derivative<br />
**[[1df1]] - m-iNOS OD+ urea derivative<br />
**[[3dwj]] – m-iNOS OD (mutant)<br />
**[[1qom]], [[4js9]] - m-iNOS OD<br />
**[[1qw4]], [[1dwv]], [[1dww]], [[1dwx]], [[1nod]] – m-iNOS OD+arginine derivative<br />
**[[2nos]] – m-iNOS OD+guanidine derivative<br />
**[[1n2n]] – m-iNOS OD+CN<br />
**[[1m9t]] – m-iNOS OD+indazole derivative<br />
**[[1m8d]] – m-iNOS OD+chlorzoxazone<br />
**[[1m8e]], [[1m8h]], [[1m8i]], [[1m9m]], [[1m9q]] – m-iNOS OD+ indazole derivative<br />
**[[1jwj]] – m-iNOS OD + inhibitor<br />
**[[1jwk]] - m-iNOS OD (mutant) + inhibitor<br />
**[[3gof]] - c-iNOS OD + calmodulin – chicken<br />
*Prokaryote NOS
**[[2amo]] – BsNOS – ''Bacillus subtilis''<br />
**[[2an0]], [[2an2]] – BsNOS (mutant)<br />
**[[2fbz]], [[2fc2]], [[2fc1]] – BsNOS+NO<br />
**[[1m7v]], [[1m7z]] – BsNOS+THF+arginine<br />
**[[5g67]], [[5g6q]], [[5g6p]], [[5g6o]], [[5g6n]], [[5g6m]], [[5g6l]], [[5g6k]], [[5g6j]], [[5g6i]], [[5g6h]], [[5g6g]], [[5g6f]], [[5g6e]], [[5g6d]], [[5g6c]], [[5g6b]], [[5g6a]], [[5g69]], [[5g68]], [[5g66]], [[5g65]], [[4ugl]], [[4uqs]], [[4uqr]], [[4ugy]], [[4ugx]], [[4ugw]], [[4ugv]], [[4ugu]], [[4ugt]], [[4ugs]], [[4ugr]], [[4ugq]], [[4ugp]], [[4ugo]], [[4ugn]], [[4ugm]], [[4ugk]], [[4ugj]], [[4ugi]], [[4ugh]], [[4ugg]], [[4ugf]], [[4uge]], [[4ugd]], [[4ugc]], [[4ugb]], [[4uga]], [[4ug9]], [[4ug8]], [[4ug7]], [[4ug6]], [[4ug5]], [[4lwb]], [[4lwa]], [[4d7j]], [[4d7i]], [[4d7h]], [[4d3v]], [[4d3u]], [[4d3t]], [[4d3o]], [[4d3n]], [[4d3m]], [[4d3k]], [[4d3j]], [[4d3i]] – BsNOS (mutant)  + inhibitor<br />
**[[2flq]] – NOS+arginine – ''Geobacillus stearothermophilus''<br />
}}
==References==
==References==
<references/>
<references/>


[[Category:Topic Page]]
[[Category:Topic Page]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michael Skovbo Windahl, Sara Toftegaard Petersen, Mathilde Thomsen, Mette Trauelsen, Eran Hodis, Jaime Prilusky, Karl Oberholser, Alexander Berchansky, Michal Harel, Ann Taylor
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