6oq9: Difference between revisions

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==Solution structure of VEK50 in the bound form with plasminogen kringle 2==
==Solution structure of VEK50 in the bound form with plasminogen kringle 2==
<StructureSection load='6oq9' size='340' side='right'caption='[[6oq9]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
<StructureSection load='6oq9' size='340' side='right'caption='[[6oq9]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6oq9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_scarlatinae"_klein_1884 "micrococcus scarlatinae" klein 1884]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OQ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OQ9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6oq9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OQ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6OQ9 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pam, emm ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1314 "Micrococcus scarlatinae" Klein 1884])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6oq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6oq9 OCA], [https://pdbe.org/6oq9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6oq9 RCSB], [https://www.ebi.ac.uk/pdbsum/6oq9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6oq9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6oq9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6oq9 OCA], [http://pdbe.org/6oq9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6oq9 RCSB], [http://www.ebi.ac.uk/pdbsum/6oq9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6oq9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PAM_STRPY PAM_STRPY]] Binds to human plasminogen (and plasmin) via its kringle repeats. Also binds to albumin, immunoglobulin G and fibrinogen. Could provide the bacteria with a mechanism for invasion, as streptococcal-bound plasmin could permit tissue penetration.  
[https://www.uniprot.org/uniprot/PAM_STRPY PAM_STRPY] Binds to human plasminogen (and plasmin) via its kringle repeats. Also binds to albumin, immunoglobulin G and fibrinogen. Could provide the bacteria with a mechanism for invasion, as streptococcal-bound plasmin could permit tissue penetration.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Micrococcus scarlatinae klein 1884]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Castellino, F J]]
[[Category: Streptococcus pyogenes]]
[[Category: Yuan, Y]]
[[Category: Castellino FJ]]
[[Category: Blood clotting]]
[[Category: Yuan Y]]
[[Category: Plasminogen binding peptide]]
[[Category: Protein binding]]

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