|
|
| Line 17: |
Line 17: |
| </StructureSection> | | </StructureSection> |
|
| |
|
| ==3D structures of integrin==
| |
|
| |
| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| |
| {{#tree:id=OrganizedByTopic|openlevels=0|
| |
|
| |
| *IG CR3
| |
|
| |
| **[[1ido]] – hIG I domain + Mg – human<br />
| |
| **[[1jlm]] - hIG I domain + Mn<br />
| |
|
| |
| *IG CD11a or IG α-L
| |
|
| |
| **[[1lfa]] - hIG I domain + Mn<br />
| |
| **[[1zon]] - hIG I domain<br />
| |
| **[[1zoo]], [[1zop]], [[3f74]] - hIG I domain + Mg<br />
| |
| **[[1mq9]] - hIG I domain (mutant) + Mn<br />
| |
| **[[1mjn]] - hIG I domain (mutant) + Mg<br />
| |
| **[[1mqa]] - hIG I domain (mutant) <br />
| |
| **[[2k8o]] – hIG cytoplasmic domain (mutant) – NMR<BR />
| |
|
| |
| *''IG CD11a complexes''
| |
|
| |
| **[[1cqp]] - hIG I domain + lovastatin + Mg<br />
| |
| **[[1mq8]], [[3bn3]], [[3tcx]] - hIG I domain (mutant) + intracellular adhesion molecule + Mg<br />
| |
| **[[1t0p]] - hIG I domain + intracellular adhesion molecule-3 + Mg<br />
| |
| **[[1rd4]], [[2ica]], [[3bqm]], [[3bqn]], [[3e2m]] - hIG I domain + inhibitor<br />
| |
| **[[2o7n]], [[3m6f]] - hIG I domain + antagonist<br />
| |
| **[[1xdd]], [[1xdg]], [[1xuo]] - hIG I domain + inhibitor + Mg<br />
| |
| **[[4ixd]] - hIG I domain + activator + Mg<br />
| |
| **[[3f78]] - hIG I domain + anesthetic + Mg<br />
| |
| **[[3eoa]], [[3eob]] - hIG I domain + antibody<br />
| |
| **[[3hi6]] - hIG I domain (mutant) + antibody + Mn<br />
| |
|
| |
| *IG CD11b
| |
|
| |
| **[[1bho]] - hIG I domain + Mg<br />
| |
| **[[1bhq]] - hIG I domain + Cd<br />
| |
| **[[1m1u]] - hIG I domain (mutant) + Ca<br />
| |
| **[[1n9z]] - hIG I domain (mutant) + Mg<br />
| |
| **[[1idn]], [[1na5]] - hIG I domain<br />
| |
| **[[1mf7]] - hIG I domain (mutant)
| |
|
| |
| *IG CD11c
| |
|
| |
| **[[1n3y]] - hIG I domain (mutant)
| |
|
| |
| *IG α-1 (CD49a)
| |
|
| |
| **[[1ck4]] - rIG I domain – rat<br />
| |
| **[[4a0q]] - hIG I domain (mutant) + Mg<br />
| |
| **[[2l8s]] - hIG transmembrane domain – NMR<BR />
| |
| **[[5hgj]] - hIG VWFA domain<br />
| |
| **[[1mhp]] - rIG I domain (mutant) + antibody + Mn<br />
| |
| **[[2b2x]] - rIG I domain (mutant) + antibody + Mg<br />
| |
| **[[2m32]] - hIG I domain + collagen peptide<br />
| |
|
| |
| *IG α-2 (CD49b)
| |
|
| |
| **[[4bj3]], [[5e6x]], [[5e6v]] - hIG I domain<br />
| |
| **[[1dzi]], [[4bj3]] - hIG I domain + collagen peptide<br />
| |
| **[[1v7p]] - hIG I domain (mutant) + EMS16 + Mn<br />
| |
| **[[5thp]], [[6nd8]], [[6nd9]], [[6nda]], [[6ndb]], [[6ndc]], [[6ndd]], [[6nde]], [[6ndf]], [[6ndg]], [[6ndh]] - hIG residues 170-366 + rhodocetin <br />
| |
|
| |
| *IG α-2b
| |
|
| |
| **[[2k1a]] - hIG transmembrane domain – NMR<BR />
| |
|
| |
| *IG α-1 β-1 (CD49a-CD49b)
| |
|
| |
| **[[1qc5]], [[1qcy]] - hIG I domain (mutant) + Mg<br />
| |
| **[[1pt6]] - hIG I domain + Mg<br />
| |
|
| |
| *IG α-2 (CD49b) β
| |
|
| |
| **[[5hj2]] - hIG I domain<br />
| |
| **[[1aox]] - hIG I domain (mutant) + Mg<br />
| |
| **[[2k1a]] - hIG transmembrane domain – NMR<br />
| |
|
| |
| *IG α-2b β-3 (CD61)
| |
|
| |
| **[[1kup]], [[1kuz]] – hIG proximal domain – NMR<BR />
| |
| **[[1m8o]] - hIG cytoplasmic domain – NMR<BR />
| |
| **[[4cak]] – hIG – Cryo-EM<br />
| |
| **[[2k9j]], [[2knc]] - hIG transmembrane domain – NMR<BR />
| |
| **[[1tye]], [[3fcu]], [[3fcs]] – hIG + Mg<br />
| |
| **[[3fc3]] – hIG (mutant) + Mg<br />
| |
| **[[2vc2]], [[2vdk]], [[2vdl]], [[3nid]], [[3nif]], [[3nig]], [[3zdx]], [[3zdy]], [[3zdz]], [[3ze0]], [[3ze1]], [[3ze2]], [[5hdb]] – hIG headpiece + antibody + Mg<br />
| |
| **[[4z7q]], [[4z7o]], [[4z7n]] – hIG headpiece + antibody + Mg + tetrapeptide<br />
| |
| **[[2vdm]], [[2vdn]], [[3t3m]], [[3t3p]] – hIG headpiece + antibody + antagonist + Mg<br />
| |
| **[[2vdo]], [[2vdp]], [[2vdq]], [[2vdr]] – hIG headpiece + antibody + fibrinogen peptide + Mg<br />
| |
|
| |
| *IG α-4
| |
|
| |
| **[[4irz]] - hIG + antibody <br />
| |
|
| |
| *IG α-4 (CD49d) β-7
| |
|
| |
| **[[3v4p]] - hIG headpiece (mutant) + antibody + Mg<br />
| |
| **[[3v4v]] - hIG headpiece (mutant) + antibody + inhibitor + Mg<br />
| |
|
| |
| *IG α-5 (CD49e) β-1 (CD29)
| |
|
| |
| **[[4wjk]] - hIG headpiece (mutant) + Mg<br />
| |
| **[[4wk0]], [[4wk2]], [[4wk4]] - hIG headpiece (mutant) + peptide + Mg<br />
| |
| **[[3vi3]] - hIG headpiece + antibody + Mg<br />
| |
| **[[3vi4]] - hIG headpiece + antibody + peptide + Mg<br />
| |
|
| |
| *IG α-5 (CD49e) β-3 (CD61) ectodomain
| |
|
| |
| **[[3ije]], [[1m1x]], [[4g1e]], [[4g1m]], [[1u8c]] – hIG + cation<br />
| |
| **[[4mmx]], [[4mmy]], [[4mmz]] - hIG + Mn + fibronectin domain 10<br />
| |
| **[[4o02]], [[6avu]], [[6avr]], [[6avq]] - hIG + antibody<br />
| |
| **[[1jv2]] - hIG + platelet membrane glycoprotein IIIA + Ca<br />
| |
| **[[1l5g]] - hIG + tripeptide + Mn<br />
| |
|
| |
| *IG α-5 β-6
| |
|
| |
| **[[4um8]] – hIG headpiece (mutant) + Ni<br />
| |
| **[[5ffg]] – hIG headpiece + Ca<br />
| |
| **[[4um9]] – hIG headpiece (mutant) + Mg + transforming growth factor β 3<br />
| |
| **[[5neu]], [[5net]], [[5ner]], [[5nem]] – hIG headpiece + foot-and-mouth virus – Cryo EM<br />
| |
| **[[5ffo]] – hIG headpiece + TGF-beta-1<br />
| |
|
| |
| *IG α-L
| |
|
| |
| **[[4ixd]] – hIG I domain<br />
| |
| **[[5e6s]], [[5e6r]] – hIG AI, headpiece,pocket domains + Mg<br />
| |
| **[[2m3e]] – hIG transmembrane domain - NMR<br />
| |
|
| |
| *IG α-L β-2
| |
|
| |
| **[[5e6u]] – hIG headpiece (mutant) + Ni<br />
| |
|
| |
| *IG α-M
| |
|
| |
| **[[3q3g]], [[3qa3]] – hIG + antibody<br />
| |
| **[[4m76]] – hIG + complement C3<br />
| |
| **[[2lke]], [[2lkj]] – hIG cytoplasmic domain – NMR<BR />
| |
| **[[4xw2]] – hIG + simvastatin<br />
| |
|
| |
| *IG α-V β-8
| |
|
| |
| **[[6djp]] – hIG + antibody – Cryo EM<br />
| |
|
| |
| *IG α-X
| |
|
| |
| **[[2luv]] – hIG cytoplasmic domain – NMR<BR />
| |
|
| |
| *IG α-X β-2 (CD18)
| |
|
| |
| **[[3k6s]], [[3k71]], [[3k72]], [[5es4]] – hIG + Mg<br />
| |
| **[[4neh]], [[4nen]] – hIG (mutant) + Mg<br />
| |
|
| |
| *IG β-1D
| |
|
| |
| **[[3g9w]] – hIG cytoplasmic tail + talin 2 F2-F3 domain<br />
| |
|
| |
| *IG β-2 (CD18)
| |
|
| |
| **[[2p26]], [[2p28]], [[5e6w]] – hIG phe2 + phe3 domains<br />
| |
| **[[1yuk]] – hIG chain A PSI domain + chain B I-EGF domain<br />
| |
| **[[5zaz]] – hIG transmembrane domain - NMR<br />
| |
|
| |
| *IG β-3 (CD61)
| |
|
| |
| **[[1s4x]], [[2kv9]], [[2ljd]], [[2lje]], [[2ljf]] – hIG cytoplasmic domain – NMR<BR />
| |
| **[[2rmz]], [[2rn0]] – hIG transmembrane domain – NMR<BR />
| |
| **[[2l91]] - hIG transmembrane domain (mutant) – NMR<BR />
| |
| **[[2l1c]] – hIG cytoplasmic tail + SHC<br />
| |
| **[[2mtp]] – hIG cytoplasmic tail (mutant) + hIG α-2 β peptide+ filamin rod domain<br />
| |
|
| |
| *IG β-4 (CD104; Gp150)
| |
|
| |
| **[[2f7q]], [[3f7r]], [[1qg3]], [[3f7q]], [[4wtw]], [[4wtx]] - hIG fibronectin type III domain<br />
| |
| **[[2yrz]] – hIG fibronectin type III domain – NMR<BR />
| |
| **[[3f7p]], [[4q58]] - hIG fibronectin type III domain + plectin-1 <br />
| |
| **[[6gvl]] - hIG fibronectin type III domain + dystonin<br />
| |
| **[[6gvk]] - hIG fibronectin type III domain (mutant) + dystonin<br />
| |
| **[[3fq4]], [[3fso]], [[3h6a]] – hIG Calx-β domain<br />
| |
| **[[6hyf]] - rIG fibronectin type III domain <br />
| |
|
| |
| *IG β-7
| |
|
| |
| **[[2brq]], [[2jf1]] – hIG cytoplasmic tail + filamin rod domain<br />
| |
|
| |
| }}
| |
| == References == | | == References == |
| <references/> | | <references/> |
| [[Category:Topic Page]] | | [[Category:Topic Page]] |