4d6z: Difference between revisions

<table><tr><td colspan='2'>[[4d6z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D6Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D6Z FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=PK9:TERT-BUTYL+{6-OXO-6-[(PYRIDIN-3-YLMETHYL)AMINO]HEXYL}CARBAMATE'>PK9</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d6z OCA], [https://pdbe.org/4d6z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d6z RCSB], [https://www.ebi.ac.uk/pdbsum/4d6z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d6z ProSAT]</span></td></tr>

[[https://www.uniprot.org/uniprot/CP3A4_HUMAN CP3A4_HUMAN]] Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide.<ref>PMID:11159812</ref>  

[[Category: Homo sapiens]]

[[Category: Poulos T]]

[[Category: Sevrioukova I]]