3md3: Difference between revisions
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<StructureSection load='3md3' size='340' side='right'caption='[[3md3]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='3md3' size='340' side='right'caption='[[3md3]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3md3]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3md3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MD3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MD3 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3md3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3md3 OCA], [https://pdbe.org/3md3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3md3 RCSB], [https://www.ebi.ac.uk/pdbsum/3md3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3md3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PUB1_YEAST PUB1_YEAST] May be associated with hnRNA within the nucleus and remains associated during nucleocytoplasmic mRNA transport, once the proteins are in the cytoplasm, disassembly of PUB1-RNA complexes may occur prior to PAB1 binding and formation of a translationally competent RNP complex. Binds to polyadenylated RNA; prefers to bind poly(rU); binds to T-rich single-stranded DNA. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Li | [[Category: Li H]] | ||
[[Category: Niu | [[Category: Niu L]] | ||
[[Category: Shi | [[Category: Shi H]] | ||
[[Category: Teng | [[Category: Teng M]] | ||
[[Category: Wang | [[Category: Wang H]] | ||
[[Category: Zhu | [[Category: Zhu Z]] | ||
Latest revision as of 11:31, 20 March 2024
Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1)Crystal Structure of the First Two RRM Domains of Yeast Poly(U) Binding Protein (Pub1)
Structural highlights
FunctionPUB1_YEAST May be associated with hnRNA within the nucleus and remains associated during nucleocytoplasmic mRNA transport, once the proteins are in the cytoplasm, disassembly of PUB1-RNA complexes may occur prior to PAB1 binding and formation of a translationally competent RNP complex. Binds to polyadenylated RNA; prefers to bind poly(rU); binds to T-rich single-stranded DNA. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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