6mq7: Difference between revisions

<table><tr><td colspan='2'>[[6mq7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MQ7 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mq7 OCA], [https://pdbe.org/6mq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mq7 RCSB], [https://www.ebi.ac.uk/pdbsum/6mq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mq7 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/CLAP1_HUMAN CLAP1_HUMAN] Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.<ref>PMID:11290329</ref> <ref>PMID:12837247</ref> <ref>PMID:15631994</ref> <ref>PMID:16866869</ref> <ref>PMID:16914514</ref> <ref>PMID:17543864</ref>  

[[Category: Homo sapiens]]

[[Category: Leano JB]]

[[Category: Slep KC]]