3cm9: Difference between revisions

<table><tr><td colspan='2'>[[3cm9]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CM9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CM9 FirstGlance]. <br>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cm9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cm9 OCA], [http://pdbe.org/3cm9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cm9 RCSB], [http://www.ebi.ac.uk/pdbsum/3cm9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cm9 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/PIGR_HUMAN PIGR_HUMAN]] This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. [[http://www.uniprot.org/uniprot/IGHA2_HUMAN IGHA2_HUMAN]] Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.