Kdo-8-phosphate synthase: Difference between revisions

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== Function ==
== Function ==
'''Kdo-8-phosphate synthase''' (KPS) catalyzes the formation of the phosphorylated rare sugar Kdo-8-phosphate (Kdo-8-P) from phosphoenolpyruvate (PEP) and D-arabinose-5-phosphate (A5P).  Some bacteria like ''Aquifex aeolicus'' have '''Metallo KPS''' which is a metal-requiring enzyme while others like ''E.coli'' have a '''Non-metallo KPS''' which does not require a divalent cation for its activity.  Kdo-8-P is found in cell walls of higher plants and some green algae<ref>PMID:11904225</ref>.
'''Kdo-8-phosphate synthase''' or '''2-dehydro-3-deoxyphosphooctonate aldolase''' (KPS) catalyzes the formation of the phosphorylated rare sugar Kdo-8-phosphate (Kdo-8-P) from phosphoenolpyruvate (PEP) and D-arabinose-5-phosphate (A5P).  Some bacteria like ''Aquifex aeolicus'' have '''Metallo KPS''' which is a metal-requiring enzyme while others like ''E.coli'' have a '''Non-metallo KPS''' which does not require a divalent cation for its activity.  Kdo-8-P is found in cell walls of higher plants and some green algae<ref>PMID:11904225</ref>.


== Structural highlights ==
== Structural highlights ==

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Michal Harel, Alexander Berchansky, Joel L. Sussman