5a66: Difference between revisions

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<StructureSection load='5a66' size='340' side='right'caption='[[5a66]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='5a66' size='340' side='right'caption='[[5a66]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5a66]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A66 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A66 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5a66]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A66 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3PO:TRIPHOSPHATE'>3PO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PO:TRIPHOSPHATE'>3PO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5a5y|5a5y]], [[5a60|5a60]], [[5a61|5a61]], [[5a64|5a64]], [[5a65|5a65]], [[5a67|5a67]], [[5a68|5a68]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a66 OCA], [https://pdbe.org/5a66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a66 RCSB], [https://www.ebi.ac.uk/pdbsum/5a66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a66 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a66 OCA], [http://pdbe.org/5a66 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a66 RCSB], [http://www.ebi.ac.uk/pdbsum/5a66 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a66 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TTM3_ARATH TTM3_ARATH]] Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi), however it does not display significant activity towards long-chain polyphosphates. The existence of PPPi in living cells is still unclear, and PPPase activity might be the ancestral function of CYTH domain. It also has gamma-phosphatase activity on NTP substrates, but no adenylate cyclase or RNA triphosphatase activity.<ref>PMID:24004165</ref>
[https://www.uniprot.org/uniprot/TTM3_ARATH TTM3_ARATH] Involved in the hydrolysis of the beta-gamma-phosphoanhydride linkage of triphosphate-containing substrates (inorganic or nucleoside-linked). Catalyzes the hydrolysis of inorganic triphosphate (PPPi), however it does not display significant activity towards long-chain polyphosphates. The existence of PPPi in living cells is still unclear, and PPPase activity might be the ancestral function of CYTH domain. It also has gamma-phosphatase activity on NTP substrates, but no adenylate cyclase or RNA triphosphatase activity.<ref>PMID:24004165</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hothorn, M]]
[[Category: Hothorn M]]
[[Category: Martinez, J]]
[[Category: Martinez J]]
[[Category: Truffault, V]]
[[Category: Truffault V]]
[[Category: Hydrolase]]
[[Category: Inorganic polyphosphate]]
[[Category: Triphosphate tunnel metalloenzyme]]
[[Category: Tripolyphosphate]]

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