6ojh: Difference between revisions
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==Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with (R)-7-(3-aminopyrrolidin-1-yl)-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine== | |||
<StructureSection load='6ojh' size='340' side='right'caption='[[6ojh]], [[Resolution|resolution]] 2.05Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ojh]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OJH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OJH FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MV4:7-[(3R)-3-aminopyrrolidin-1-yl]-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine'>MV4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ojh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ojh OCA], [http://pdbe.org/6ojh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ojh RCSB], [http://www.ebi.ac.uk/pdbsum/6ojh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ojh ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ACCC_HAEIN ACCC_HAEIN]] This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Andrews, L D]] | |||
[[Category: Cirz, R]] | |||
[[Category: Cohen, F]] | |||
[[Category: Dozzo, P]] | |||
[[Category: Haglund, C M]] | |||
[[Category: Hilderbrandt, D J]] | |||
[[Category: Kane, T R]] | |||
[[Category: Linsell, M S]] | |||
[[Category: Machajewski, T]] | |||
[[Category: McEnroe, G]] | |||
[[Category: Neau, D B]] | |||
[[Category: Pakhomova, S]] | |||
[[Category: Pogliano, J]] | |||
[[Category: Serio, A W]] | |||
[[Category: Sharp, M]] | |||
[[Category: Waldrop, G L]] | |||
[[Category: Wlasichuk, K B]] | |||
[[Category: Atp grasp]] | |||
[[Category: Carboxylase]] | |||
[[Category: Inhibitor]] | |||
[[Category: Ligase]] |