6d4w: Difference between revisions

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-'''Unreleased structure'''
-The entry 6d4w is ON HOLD  until Paper Publication
+==M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 35 (VCC620637)==
+<StructureSection load='6d4w' size='340' side='right'caption='[[6d4w]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-Authors: Ascher, D.B., Pacitto, A., Blundell, T.L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6d4w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D4W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D4W FirstGlance]. <br>
-Description: M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 35 (VCC620637)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FWJ:2-(4-fluorophenyl)-1-{4-[(isoquinolin-5-yl)sulfonyl]piperazin-1-yl}ethan-1-one'>FWJ</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d4w OCA], [http://pdbe.org/6d4w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d4w RCSB], [http://www.ebi.ac.uk/pdbsum/6d4w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d4w ProSAT]</span></td></tr>
-[[Category: Blundell, T.L]]
+</table>
-[[Category: Ascher, D.B]]
+== Function ==
+[[http://www.uniprot.org/uniprot/G7CNL4_MYCT3 G7CNL4_MYCT3]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Ascher, D B]]
+[[Category: Blundell, T L]]
 [[Category: Pacitto, A]]
+[[Category: Complex]]
+[[Category: Fragment]]
+[[Category: Impdh]]
+[[Category: Oxidoreductase]]
+[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]