6d4q: Difference between revisions
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==M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 14 (VCC900455)== | |||
<StructureSection load='6d4q' size='340' side='right'caption='[[6d4q]], [[Resolution|resolution]] 1.71Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6d4q]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D4Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D4Q FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FWG:cycloheptyl{4-[(isoquinolin-5-yl)sulfonyl]piperazin-1-yl}methanone'>FWG</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d4q OCA], [http://pdbe.org/6d4q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d4q RCSB], [http://www.ebi.ac.uk/pdbsum/6d4q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d4q ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/G7CNL4_MYCT3 G7CNL4_MYCT3]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Ascher, D B]] | |||
[[Category: Blundell, T L]] | |||
[[Category: Pacitto, A]] | [[Category: Pacitto, A]] | ||
[[Category: Complex]] | |||
[[Category: Fragment]] | |||
[[Category: Impdh]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]] | |||
Revision as of 11:43, 1 May 2019
M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 14 (VCC900455)M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 14 (VCC900455)
Structural highlights
Function[G7CNL4_MYCT3] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] |
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